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Review
. 2022 Feb;10(1):e00909.
doi: 10.1002/prp2.909.

Molnupiravir: A new candidate for COVID-19 treatment

Affiliations
Review

Molnupiravir: A new candidate for COVID-19 treatment

Fariba Pourkarim et al. Pharmacol Res Perspect. 2022 Feb.

Abstract

The novel coronavirus disease 2019 (COVID-19) emerged in late December 2019 in china and has rapidly spread to many countries around the world. The effective pharmacotherapy can reduce the mortality of COVID-19. Antiviral medications are the candidate therapies for the management of COVID-19. Molnupiravir is an antiviral drug with anti-RNA polymerase activity and currently is under investigation for the treatment of patients with COVID-19. This review focuses on summarizing published literature for the mechanism of action, safety, efficacy, and clinical trials of molnupiravir in the treatment of COVID-19 patients.

Keywords: COVID-19 treatment; EIDD-2801; MK-4482; antiviral drugs; molnupiravir; novel coronavirus disease 2019.

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Conflict of interest statement

The authors declare that there is no conflict of interest.

References

    1. Lu H, Stratton CW, Tang YW. Outbreak of pneumonia of unknown etiology in Wuhan, China: the mystery and the miracle. J Med Virol. 2020;92(4):401‐402. - PMC - PubMed
    1. Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet. 2020;395(10223):497‐506. - PMC - PubMed
    1. Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. The Lancet. 2020;395(10223):507‐513. - PMC - PubMed
    1. Wang C, Horby PW, Hayden FG, Gao GF. A novel coronavirus outbreak of global health concern. Lancet. 2020;395(10223):470‐473. - PMC - PubMed
    1. Baradaran H, Hamishehkar H, Rezaee H. NSAIDs and COVID‐19: a new challenging area. Pharm Sci. 2020;26(Suppl 1):S49‐S51.

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