Ischaemic colitis in a patient treated with glypressin for bleeding oesophageal varices

Abstract

This paper reports a case of ischaemic colitis observed in a male patient with acute oesophageal variceal bleeding treated with Glypressin (triglycyl lysine vasopressin). The therapeutic effect of this substance depends on the lowering of the portal vein pressure brought about by a vasoconstriction of the vessels of the splanchnic region. The undesired complication of ischaemic colitis occurred as a result of a reduction in blood flow to the colonic mucosa.