Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Feb;114(1):47-55.
doi: 10.1016/j.jnma.2021.12.003. Epub 2021 Dec 29.

Acute Mesenteric Ischemia in Patients with COVID-19: Review of the literature

Can Chen  1 , Yi-Wei Li  2 , Peng-Fei Shi  1 , Shen-Xian Qian  3
Affiliations
Review

Acute Mesenteric Ischemia in Patients with COVID-19: Review of the literature

Can Chen et al. J Natl Med Assoc. 2022 Feb.

Abstract

The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in a global health emergency. In addition to common respiratory symptoms, some patients with COVID-19 infections may experience a range of extra-pulmonary manifestations, such as digestive system involvement. Patients with COVID-19 have been reported to suffer from acute mesenteric ischemia (AMI) that is associated with disease-related severity and mortality. However, in the context of COVID-19, the exact cause of AMI has yet to be clearly defined. This review provides a comprehensive overview of the available data and elucidates the possible underlying mechanisms linking COVID-19 to AMI, in addition to highlighting therapeutic approaches for clinicians. Finally, given the severe global impact of COVID-19, we emphasize the importance of coordinated vaccination programs.

Keywords: Acute mesenteric ischemia; COVID-19; Gastrointestinal disorders; SARS-CoV-2; Therapy.

PubMed Disclaimer

References

    1. Huang C., Wang Y., Li X., et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497–506. doi: 10.1016/S0140-6736(20)30183-5. - DOI - PMC - PubMed
    1. Avila J., Long B., Holladay D., Gottlieb M. Thrombotic complications of COVID-19. Am J Emerg Med. 2021;39:213–218. doi: 10.1016/j.ajem.2020.09.065. - DOI - PMC - PubMed
    1. Clair DG., Beach JM. Mesenteric Ischemia. N Engl J Med. 2016;374(10):959–968. doi: 10.1056/NEJMra1503884. - DOI - PubMed
    1. Kärkkäinen JM., Acosta S. Acute mesenteric ischemia (part I) - incidence, etiologies, and how to improve early diagnosis. Best Pract Res Clin Gastroenterol. 2017;31(1):15–25. doi: 10.1016/j.bpg.2016.10.018. - DOI - PubMed
    1. Acosta S. Epidemiology of mesenteric vascular disease: clinical implications. Semin Vasc Surg. 2010;23(1):4–8. doi: 10.1053/j.semvascsurg.2009.12.001. - DOI - PubMed