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Review
. 2021 Dec;113(6):436-441.
doi: 10.32074/1591-951X-197.

Recurrent primary endobronchial fetal rhabdomyoma: a case report and literature review

Stefano Marletta  1 , Anna Caliò  1 , Adele Fioravanzo  1 , Enrico Cavallo  1 , Evelin Torresani  1 , Federica Zampieri  1 , Eliana Gilioli  2
Affiliations
Review

Recurrent primary endobronchial fetal rhabdomyoma: a case report and literature review

Stefano Marletta et al. Pathologica. 2021 Dec.

Abstract

Fetal rhabdomyoma is an extremely rare benign rhabdomyoblastic tumor with myotube-like differentiation, mainly arising on mucosal surfaces of the head and neck region of both children and young patients, almost invariably definitively treated with surgical excision. Herein the case of a male adult suffering from a recurrent fetal rhabdomyoma primary involving the bronchial structures is reported, along with a detailed literature review. This is the first fetal rhabdomyoma described to originate in such a localization; furthermore, an 11-year interval period between the first lesion and the recurrent one has never been reported.

Keywords: benign mesenchymal neoplasm; endobronchial; fetal rhabdomyoma; recurrence; skeletal muscle differentiation.

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Conflict of interest statement

Conflict of interest

The Authors declare no conflict of interest.

Figures

Figure 1.
Figure 1.
Low (A) and high (B) power magnification showing fascicles of tumor cells, highlighted by the arrows, embedded in a myxoid stroma.
Figure 2.
Figure 2.
Low (A) and high (B) power view of the recurrent lesion with a cell-poor area, characterized by a few oval rabdomyoblastic cells embedded within a loose connective tissue, intermingled with a more cellular focus of spindled cells haphazardly arranged in irregular bundles.
Figure 3.
Figure 3.
Myogenic differentiation of the recurrent lesion is confirmed by positive staining for muscle specific actin (A) and desmin (B).
See this image and copyright information in PMC

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