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Comment
. 2022 Jan;24(1):101-103.
doi: 10.1016/j.jmoldx.2021.10.002.

The Prognostic Value of an RT-PCR Test for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Is Contingent on Timing across Disease Time Course in addition to Assay Sensitivity

Jeffrey P Townsend  1 , Chad R Wells  2
Affiliations
Comment

The Prognostic Value of an RT-PCR Test for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Is Contingent on Timing across Disease Time Course in addition to Assay Sensitivity

Jeffrey P Townsend et al. J Mol Diagn. 2022 Jan.
No abstract available

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Figures

Figure 1
Figure 1
Sensitivity of RT-PCR for detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) across the COVID-19 disease time course from infection. The approximately 3.5-day period during which students surveilled in the study by Tian et al are likely to first test positive spans a rapid rise in viral load early in disease. Sensitivity when sampling only symptomatic cases (green) is based on Miller et al, He et al,, and Qin et al using the approach of Wells et al. Sensitivity when sampling currently asymptomatic cases (blue) is based on data from Hellewell et al, He et al,, and Qin et al using the approach of Wells et al.
See this image and copyright information in PMC

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  • Authors' Reply.
    Tian D, Lin Z, Kriner EM, Esneault DJ, Tran J, DeVoto JC, Okami N, Greenberg R, Yanofsky S, Ratnayaka S, Tran N, Livaccari M, Lampp M, Wang N, Tim S, Norton P, Scott J, Hu TY, Garry R, Hamm L, Delafontaine P, Yin XM. Tian D, et al. J Mol Diagn. 2022 Jan;24(1):103. doi: 10.1016/j.jmoldx.2021.10.003. J Mol Diagn. 2022. PMID: 34974876 Free PMC article. No abstract available.

Comment on

References

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