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. 2021 Feb;20(2):156-163.

Clinical and Epidemiological Characteristics of Coronavirus Disease 2019 in Iran: a Hospital-Based Observational Study

Ilad Alavi Darazam  1   2 , Sajad Besharati  1   2 , Minoosh Shabani  1   2 , Shervin Shokouhi  1   2 , Mohammad Fallahzadeh  1   2 , Hadiseh Shabanpour Dehbsneh  1 , Negar Khalili  1 , Azam Soleymaninia  1 , Akram Hoseyni Kusha  1 , Maryam Taleb Shoushtari  1 , Mahdi Amirdosara  3 , Mohammadreza Hajiesmaeili  3 , Omidvar Rezaei  4 , Ali Khoshkar  5 , Seyed Sina Naghibi Irvani  1   2 , Mahnaz Kheyrian  1 , Fatemeh Goudarzi  6
Affiliations

Clinical and Epidemiological Characteristics of Coronavirus Disease 2019 in Iran: a Hospital-Based Observational Study

Ilad Alavi Darazam et al. Tanaffos. 2021 Feb.

Abstract

Background: Coronavirus disease 2019 (COVID-19) has been pandemic and has caused a great burden on almost all countries across the world. Different perspectives of this novel disease are poorly understood. This study sought to investigate the clinical and epidemiological characteristics of COVID-19 to efficiently assist the health system of Iran to conquer the outbreak.

Materials and methods: This retrospective observational study was performed on 394 patients with a diagnosis of COVID-19. The patients should have a history of hospitalization at Loghman-Hakim hospital, Tehran, Iran, for 10 weeks, beginning from the first official report of the disease in Iran. In the subsequent step, the baseline demographic and clinical and paraclinical information of the patients was documented. Finally, the patients were assessed if they had exhibited any morbidity or mortality.

Results: The epidemiological examination of the COVID-19 population suggested a bell diagram pattern for the hospitalization rate, in which the 4th week of the study was the peak. The highest rate of secondary adverse events due to the virus was observed at the 6th and 7th weeks of the study course. On another note, clinical evaluations resulted in identifying specific abnormalities, such as bilateral opacity in chest computed tomography scans or low oxygen saturation in laboratory data.

Conclusion: This study provides evidence concerning the clinical and epidemiological characteristics of COVID-19 in the first phase of the virus outbreak in Iran. Further studies comparing the disease features in the subsequent phases with findings of this study can pave the way for additional information in this regard.

Keywords: COVID-19; Iran; Loghman-Hakim Hospital; Morbidity; Mortality; Observational Study.

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Figures

Figure 1.
Figure 1.
Rates of admission and mortality for patients with COVID-19 diagnosis during 10 weeks
Figure 2.
Figure 2.
The most common clinical presentations of hospitalized patients with COVID-19
Figure 3.
Figure 3.
Prescription trend of antiviral drugs during the first outbreak of COVID-19 in Iran
Figure 4.
Figure 4.
The trend of COVID-19 related morbidities and mortality during the study period
See this image and copyright information in PMC

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