Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Nov 25;12(Suppl 1):S41-S54.
doi: 10.4103/idoj.idoj_290_21. eCollection 2021 Nov.

Platelet-Rich Plasma in Aesthetics

Soni Nanda  1 , Kavish Chauhan  2 , Vinma Shetty  3 , Shuken Dashore  4 , Satish Bhatia  5
Affiliations

Platelet-Rich Plasma in Aesthetics

Soni Nanda et al. Indian Dermatol Online J. .

Abstract

Platelet-rich plasma (PRP) is being used as a treatment modality for skin rejuvenation since the last decade. There has been a lot of ambiguity regarding the ideal protocol to be followed and the specific indications where its use should be promoted. The use of PRP as monotherapy for skin rejuvenation, acne scars, periorbital rejuvenation, lipofilling and in combination with fractional CO2 and other resurfacing modalities is increasing rapidly. In this article, we have reviewed the current scientific evidence available and the IADVL national task force for PRP has come up with standard recommendations for use of PRP in esthetics along with the grade of evidence and strength of recommendation for each indication. The aim of this review is to provide a standard protocol for use of PRP in esthetics, for clinicians and academicians, leading to excellent results with this promising treatment modality.

Keywords: Biofiller; esthetics; lipofilling; periorbital rejuvenation; platelet-rich plasma; recommendations; skin rejuvenation.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
(a) Open pores, uneven texture, tone. (b) Improvement in 4 weeks after 1 session
Figure 2
Figure 2
(a) Acne scars grade 2. (b) Improvement after 1 month of 2 sessions
Figure 3
Figure 3
(a) Loss of volume, tone of periorbital area. (b) Improvement seen, 1 month after 3 monthly sessions
Figure 4
Figure 4
(a) Vial for dental syringe is filled with PPP. (b) Vial kept in water bowl at 70°C –80°C. (c) Dental syringe, 27G needles. (d) Biofiller in vials. (e) Vial loaded in the dental syringe. (f) Gel-like consistency
Figure 5
Figure 5
(a) Varioliform Scar pretreatment. (b) Scar filled
See this image and copyright information in PMC

References

    1. Garcia BA, Smalley DM, Cho H, Shabanowitz J, Ley K, Hunt DF. The platelet microparticle proteome. J Proteome Res. 2005;4:1516–21. - PubMed
    1. Browning SR, Weiser AM, Woolf N, Golish SR, SanGiovanni TP, Scuderi GJ, et al. Platelet-rich plasma increases matrix metalloproteinases in cultures of human synovial fibroblasts. J Bone Joint Surg Am. 2012;94:1721–7. - PubMed
    1. Cho HS, Song IH, Park S-Y, Sung MC, Ahn M-W, Song KE. Individual variation in growth factor concentrations in platelet-rich plasma and its influence on human mesenchymal stem cells. Korean J Lab Med. 2011;31:212–8. - PMC - PubMed
    1. Alsousou J, Thompson M, Hulley P, Noble A, Willett K. The biology of platelet-rich plasma and its application in trauma and orthopaedic surgery: A review of the literature. J Bone Joint Surg Br. 2009;91:987–96. - PubMed
    1. Mautner K, Malanga GA, Smith J, Shiple B, Ibrahim V, Sampson S, et al. A call for a standard classification system for future biologic research: The rationale for new PRP nomenclature. PM R. 2015;7:S53–9. - PubMed