Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2022 Mar;3(3):e167.
doi: 10.1016/S2666-5247(21)00337-2. Epub 2021 Dec 23.

Neutralising antibody titres as predictors of protection against SARS-CoV-2 variants

Affiliations
Comment

Neutralising antibody titres as predictors of protection against SARS-CoV-2 variants

Scott J C Pallett et al. Lancet Microbe. 2022 Mar.
No abstract available

PubMed Disclaimer

Conflict of interest statement

LSPM has consulted for bioMerieux (2013–20), DNAelectronics (2015–18), Dairy Crest (2017–18), Umovis Lab (2020), and Pfizer (2018–20), received speaker fees from Profile Pharma (2018), received research grants from the National Institute of Health Research (NIHR; 2013–20), CW+ Charity (2018–19), and Leo Pharma (2016), and received educational support from Eumedica (2016–18). SJCP has received a research grant from the Scientific Exploration Society. All other authors declare no competing interests. LSPM acknowledges support from the NIHR Imperial Biomedical Research Centre and the NIHR Health Protection Research Unit in Healthcare Associated Infection and Antimicrobial Resistance at Imperial College London in partnership with Public Health England. The views expressed in this publication are those of the authors and not necessarily those of the UK National Health Service, the NIHR, or the UK Department of Health.

Comment on

References

    1. Cromer D, Steain M, Reynaldi A, et al. Neutralising antibody titres as predictors of protection against SARS-CoV-2 variants and the impact of boosting: a meta-analysis. Lancet Microbe. 2021 doi: 10.1016/S2666-5247(21)00267-6. published online Nov 15. - DOI - PMC - PubMed
    1. Bartleson JM, Radenkovic D, Covarrubias AJ, Furman D, Winer DA, Verdin E. SARS-CoV-2, COVID-19 and the aging immune system. Nat Aging. 2021;1:769–782. - PMC - PubMed
    1. De Giovanni M, Cutillo V, Giladi A, et al. Spatiotemporal regulation of type I interferon expression determines the antiviral polarization of CD4+ T cells. Nat Immunol. 2020;21:321–330. - PMC - PubMed
    1. Della-Torre E, Criscuolo E, Lanzillotta M, et al. IL-1 and IL-6 inhibition affects the neutralising activity of anti-SARS-CoV-2 antibodies in patients with COVID-19. Lancet Rheumatol. 2021;3:e829–e831. - PMC - PubMed
    1. Pallett SJC, Jones R, Abdulaal A, et al. Variability in detection of SARS-CoV-2 specific antibody responses following mild–moderate infection: a prospective multi-centre cross-sectional study London, United Kingdom, 17 April to 17 July 2020. Eurosurveillance. 2021 (in press). - PMC - PubMed

Supplementary concepts