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. 2022 Feb 22;43(8):800-806.
doi: 10.1093/eurheartj/ehab908.

The year in cardiovascular medicine 2021: acute cardiovascular care and ischaemic heart disease

Susanna Price  1   2 , Jason Katz  3 , Christoph C Kaufmann  4 , Kurt Huber  4   5   6
Affiliations

The year in cardiovascular medicine 2021: acute cardiovascular care and ischaemic heart disease

Susanna Price et al. Eur Heart J. .

Abstract

Mechanisms and clinical phenotypes: the potential impact of acute COVID-19 on the heart and its longer-term sequelae. Reprinted with permission from: Friedrich MG, Cooper LT Jr. What we (don’t) know about myocardial injury after COVID-19. Eur Heart J 2021;42:1879–1882.

Keywords: Acute cardiac care; Acute coronary syndromes; COVID-19; Cardiogenic shock; Ischaemic heart disease.

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Figures

Graphical Abstract
Graphical Abstract
Mechanisms and clinical phenotypes: the potential impact of acute COVID-19 on the heart and its longer-term sequelae. Reprinted with permission from: Friedrich MG, Cooper LT Jr. What we (don’t) know about myocardial injury after COVID-19. Eur Heart J 2021;42:1879–1882.
Figure 1
Figure 1
Key findings from the Hartiala study determining distinct genetic risk factors for MI. Here, acting on a normal vessel, known genetic risk factors for CAD lead to plaque initiation and progression; subsequently, two distinct risk factors act, resulting in plaque rupture and thrombus formation. MI, myocardial infarction; CAD, coronary artery disease. Reprinted with permission from Hartiala et al.
Figure 2
Figure 2
A graphical abstract summarizing the main features and findings of the OPTICO-ACS study. STE, ST elevation; NSTE, non-ST elevation; ACS, acute coronary syndrome; OCT, optical coherence tomography; CL, culprit lesion; IFC, intact fibrous cap; RFC, ruptured fibrous cap; NK, natural killer cell. Reprinted with permission from Leistner et al.
Figure 3
Figure 3
Key findings from a meta-analysis of five studies determining the effects of colchicine on MACE including risk reduction and potential mechanisms. MACE, major adverse cardiovascular events. Reprinted with permission from Fiolet et al.
Figure 4
Figure 4
Development of the CLIP score in cardiogenic shock. Fifty-eight parameters were studied in patients included in the IABP SHOCK II study, and with internal and external validation a simple four-point biomarker score was developed for mortality risk stratification. IABP, intra-aortic balloon pump; SAPS, simplified Apache physiological score. Reprinted with permission from Ceglarek et al.
See this image and copyright information in PMC

References

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    1. Lechner I, Reindl M, Tiller C, Holzknecht M, Troger F, Fink P, et al. . Impact of COVID-19 pandemic restrictions on ST-elevation myocardial infarction: a cardiac magnetic resonance imaging study. Eur Heart J 2021;42:ehab621. - PMC - PubMed
    1. Tokarek T, Dziewierz A, Malinowski K, Rakowski T, Bartus S, Dudek D, et al. . Treatment delay and clinical outcomes in patients with ST-elevation myocardial infarction during the COVID-19 pandemic. Eur Heart J 2021;42(Suppl 1):ehab724.1470. - PMC - PubMed
    1. Kubica-Malgorzata J, Wioleta O, Stolarek M, Kasprzak M, Grzelakowska K, Kryś J, et al. . Impact of COVID-19 pandemic on acute heart failure admissions and mortality: a multicentre study (COV-HF-SIRIO 6 study). ESC Heart Fail 2021;doi: 10.1002/ehf2.13680. - DOI - PMC - PubMed
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