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Meta-Analysis
. 2022 Dec;26(4):1539-1550.
doi: 10.1007/s11325-021-02520-y. Epub 2022 Jan 3.

Lateral pharyngoplasty vs. traditional uvulopalatopharyngoplasty for patients with OSA: systematic review and meta-analysis

Antonino Maniaci  1 , Milena Di Luca  2 , Jerome René Lechien  3 , Giannicola Iannella  4   5 , Calogero Grillo  2 , Caterina Maria Grillo  2 , Federico Merlino  2 , Christian Calvo-Henriquez  6 , Andrea De Vito  4 , Giuseppe Magliulo  5 , Annalisa Pace  5 , Claudio Vicini  4   7 , Salvatore Cocuzza  2 , Vittoria Bannò  2 , Isabella Pollicina  2 , Giovanna Stilo  2 , Alberto Bianchi  8 , Ignazio La Mantia  2
Affiliations
Meta-Analysis

Lateral pharyngoplasty vs. traditional uvulopalatopharyngoplasty for patients with OSA: systematic review and meta-analysis

Antonino Maniaci et al. Sleep Breath. 2022 Dec.

Abstract

Objectives: To compare the efficacy and success rates of lateral pharyngoplasty techniques (LP) vs. uvulopalatopharyngoplasty (UPPP) among adult patients surgically treated for obstructive sleep apnea.

Methods: A systematic literature review of the last 20 years' papers was conducted using PubMed/Medline, Embase, Web of Science, Scholar, and the Cochrane Library until April 2021. Only full-text English articles comparing LP and UPPP outcomes in adult patients with objective outcomes were included in the study.

Results: We included 9 articles for a total of 312 surgically treated patients with OSA. LP techniques for obstructive sleep apnea were used on 186 (60%) subjects, while 126 patients (40%) were treated with UPPP. Both surgical procedures resulted in significant improvements in apnea-hypopnea index (AHI), Epworth Sleepiness Scale (ESS) score, and lowest oxygen saturation (LOS) (p < 0.001 in all cases). Although better outcomes were reported with lateral pharyngoplasty, the differences were not significant compared to UPPP post-operative results (p > 0.05 in all cases).

Conclusions: UPPP and LP are both effective surgical procedures in treating OSA in adults. Although not significant, LPs demonstrated improved post-operative outcomes. However, further evidence comparing the surgical effect on patients with OSA is needed to discriminate post-operative outcomes.

Keywords: Barbed reposition pharyngoplasty; Expansion sphincter pharyngoplasty; OSA surgery; Obstructive sleep apnea; Uvulopalatopharyngoplasty.

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