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Review
. 2022 Apr:74:211-219.
doi: 10.1016/j.copbio.2021.11.011. Epub 2021 Dec 31.

Bioelectrosynthesis systems

Affiliations
Review

Bioelectrosynthesis systems

Joshua Finkelstein et al. Curr Opin Biotechnol. 2022 Apr.

Abstract

Bioelectrosynthesis (BES) systems exploit extracellular electron transport pathways to augment cellular metabolism. This strategy can be used to improve the economic viability of bio-based syntheses versus conventional methods, most notably petrochemical-based syntheses. It also has the potential to reduce the carbon footprint of biomanufacturing processes. Efficient channeling of cathode-derived electrons towards biosynthesis requires a better understanding of the biological mechanisms of electron transport as well as detailed evaluation of all aspects of process performance. More advanced solutions may deploy cell free systems that use ex situ generated reducing equivalents to improve economic performance.

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