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Review
. 2022 Jan 3;23(1):26.
doi: 10.1186/s12891-021-04957-4.

Neck pain: global epidemiology, trends and risk factors

Somaye Kazeminasab  1   2 , Seyed Aria Nejadghaderi  3   4 , Parastoo Amiri  1   2 , Hojjat Pourfathi  5 , Mostafa Araj-Khodaei  1   6 , Mark J M Sullman  7   8 , Ali-Asghar Kolahi  9 , Saeid Safiri  10   11
Affiliations
Review

Neck pain: global epidemiology, trends and risk factors

Somaye Kazeminasab et al. BMC Musculoskelet Disord. .

Abstract

Background: Neck pain is one of the most common musculoskeletal disorders, having an age-standardised prevalence rate of 27.0 per 1000 population in 2019. This literature review describes the global epidemiology and trends associated with neck pain, before exploring the psychological and biological risk factors associated with the initiation and progression of neck pain.

Methods: The PubMed database and Google Scholar search engine were searched up to May 21, 2021. Studies were included that used human subjects and evaluated the effects of biological or psychological factors on the occurrence or progression of neck pain, or reported its epidemiology.

Results: Psychological risk factors, such as long-term stress, lack of social support, anxiety, and depression are important risk factors for neck pain. In terms of the biological risks, neck pain might occur as a consequence of certain diseases, such as neuromusculoskeletal disorders or autoimmune diseases. There is also evidence that demographic characteristics, such as age and sex, can influence the prevalence and development of neck pain, although further research is needed.

Conclusions: The findings of the present study provide a comprehensive and informative overview that should be useful for the prevention, diagnosis, and management of neck pain.

Keywords: Epidemiology; Narrative review; Neck pain; Risk factor.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
The percentage change in age-standardised point prevalence of neck pain from 1990 to 2017 for 21 Global Burden of Disease regions by sex. (Extracted from the study published by Safiri and colleagues [5])
Fig. 2
Fig. 2
The percentage change in age-standardised annual incidence rates of neck pain from 1990 to 2017 for 21 Global Burden of Disease regions by sex. (Extracted from the study published by Safiri and colleagues [5])
Fig. 3
Fig. 3
Age standardised point prevalence of neck pain per 100,000 population in 2017, by country. (Extracted from the study published by Safiri and colleagues [5])
Fig. 4
Fig. 4
Age standardised annual incidence of neck pain per 100,000 population in 2017, by country. (Extracted from the study published by Safiri and colleagues [5])
Fig. 5
Fig. 5
Global number of incident c ases and age-standardised annual incidence rate of neck pain per 100,000 population by age and sex, 2017; Dotted and dashed lines indicate 95% upper and lower uncertainty intervals, respectively. (Extracted from the study published by Safiri and colleagues [5])
Fig. 6
Fig. 6
Summary diagram representing the biological and psychological risk factors of neck pain
See this image and copyright information in PMC

References

    1. Cohen SP. Epidemiology, diagnosis, and treatment of neck pain. Mayo Clin Proc. 2015;90(2):284–299. - PubMed
    1. Ariëns GA, van Mechelen W, Bongers PM, Bouter LM, van der Wal G. Psychosocial risk factors for neck pain: a systematic review. Am J Ind Med. 2001;39(2):180–193. - PubMed
    1. Dieleman JL, Cao J, Chapin A, Chen C, Li Z, Liu A, Horst C, Kaldjian A, Matyasz T, Scott KW. US health care spending by payer and health condition, 1996-2016. JAMA. 2020;323(9):863–884. - PMC - PubMed
    1. Lezin N, Watkins-Castillo S. The impact of musculoskeletal disorders on Americans-opportunities for action. Burden Musculoskelet Dis US Prev Soc Econ Cost. 2016;3.
    1. Safiri S, Kolahi A-A, Hoy D, Buchbinder R, Mansournia MA, Bettampadi D, et al. Global, regional, and national burden of neck pain in the general population, 1990–2017: systematic analysis of the Global Burden of Disease Study 2017. BMJ. 2020;368. - PMC - PubMed