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Review
. 2021 Nov;14(11):44-57.

Platelet-Rich Plasma: A Comprehensive Review of Emerging Applications in Medical and Aesthetic Dermatology

Christopher White  1   2 , Allyson Brahs  1   2 , David Dorton  1   2 , Kristin Witfill  1   2
Affiliations
Review

Platelet-Rich Plasma: A Comprehensive Review of Emerging Applications in Medical and Aesthetic Dermatology

Christopher White et al. J Clin Aesthet Dermatol. 2021 Nov.

Abstract

Platelet-rich plasma (PRP) has been integrated into numerous treatment regimens for medical and aesthetic dermatology. While some of these approaches are well-established, many uses are underreported in the literature. We sought to identify and summarize the emerging dermatologic applications for PRP by conducting a comprehensive PubMed search of studies published between 2000 and 2020. These studies were reviewed to synthesize collection methods, treatment schedule, adverse effects, and the impact of therapy for new and emerging uses for PRP. In general, we identified positive treatment outcomes for skin rejuvenation, scar revision, alopecia, pigmentary disorders, lichen sclerosus, leprosy-induced peripheral neuropathy, plaque psoriasis, and nail disorders. Widely, therapy was well-tolerated and suitable for all reported phototypes. The variations in collection and application sequences make concrete recommendations difficult to discern, underscoring the need for a standardized approach to preparation and treatment methods. We hope this review serves as an outline for new and interesting uses for PRP and will help readers familiarize themselves with this exciting technology for comfortable integration into their practices.

Keywords: PRP; Platelet-rich plasmas; aesthetic dermatology; emerging treatments; medical dermatology.

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Conflict of interest statement

DISCLOSURES: The authors report no conflicts of interest relevant to the content of this article.

Figures

FIGURE 1.
FIGURE 1.
The typical process for a one- or two-step PRP preparation protocol. Abbreviations: WB, whole blood; BC, buffy coat; RBC, red blood cell; PPP, platelet-poor plasma
FIGURE 2.
FIGURE 2.
Study data-collection method
See this image and copyright information in PMC

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