Skin cancer in immunosuppressed patients
- PMID: 34985005
- DOI: 10.1097/01.JAA.0000805800.77311.4c
Skin cancer in immunosuppressed patients
Abstract
The number of people living with chronic immunosuppression is increasing in the United States. Patients with HIV, those who have had bone marrow or solid organ transplants, and patients taking biologics for autoimmune diseases are at increased risk for skin cancer. Skin cancer in these patients is more aggressive and more likely to metastasize and cause death. Medications and individual risk factors such as sex, age, and ethnicity are independent risk factors for the development of skin cancer. Routine screening and aggressive treatment of actinic keratoses and nonmelanoma skin cancers can reduce patients' skin cancer burden and improve patient outcomes.
Copyright © 2022 American Academy of Physician Assistants.
Similar articles
-
Nonmelanoma Skin Cancer in Nonwhite Organ Transplant Recipients.JAMA Dermatol. 2016 Dec 1;152(12):1348-1353. doi: 10.1001/jamadermatol.2016.3328. JAMA Dermatol. 2016. PMID: 27653769
-
Immunosuppression in gastroenterology and hepatology.Best Pract Res Clin Gastroenterol. 2021 Oct-Dec;54-55:101758. doi: 10.1016/j.bpg.2021.101758. Epub 2021 Jun 17. Best Pract Res Clin Gastroenterol. 2021. PMID: 34874842 Review.
-
Cutaneous Oncology in the Immunosuppressed.Dermatol Clin. 2023 Jan;41(1):141-162. doi: 10.1016/j.det.2022.07.012. Dermatol Clin. 2023. PMID: 36410975 Review.
-
Risk of nonmelanoma skin cancer with azathioprine use.Inflamm Bowel Dis. 2008 Oct;14(10):1425-31. doi: 10.1002/ibd.20444. Inflamm Bowel Dis. 2008. PMID: 18383175 Review.
-
Skin changes following organ transplantation: an interdisciplinary challenge.Dtsch Arztebl Int. 2014 Mar 14;111(11):188-94. doi: 10.3238/arztebl.2014.0188. Dtsch Arztebl Int. 2014. PMID: 24698074 Free PMC article. Review.
Cited by
-
Can Artificial Intelligence "Hold" a Dermoscope?-The Evaluation of an Artificial Intelligence Chatbot to Translate the Dermoscopic Language.Diagnostics (Basel). 2024 May 31;14(11):1165. doi: 10.3390/diagnostics14111165. Diagnostics (Basel). 2024. PMID: 38893694 Free PMC article.
-
Photosensitizers-Loaded Nanocarriers for Enhancement of Photodynamic Therapy in Melanoma Treatment.Pharmaceutics. 2023 Aug 11;15(8):2124. doi: 10.3390/pharmaceutics15082124. Pharmaceutics. 2023. PMID: 37631339 Free PMC article. Review.
-
Molecular and Histopathological Characterization of Metastatic Cutaneous Squamous Cell Carcinomas: A Case-Control Study.Cancers (Basel). 2024 Jun 15;16(12):2233. doi: 10.3390/cancers16122233. Cancers (Basel). 2024. PMID: 38927938 Free PMC article.
-
Advancements in nanoparticle-based treatment approaches for skin cancer therapy.Mol Cancer. 2023 Jan 12;22(1):10. doi: 10.1186/s12943-022-01708-4. Mol Cancer. 2023. PMID: 36635761 Free PMC article. Review.
-
Non-Melanoma Skin Cancer: A Genetic Update and Future Perspectives.Cancers (Basel). 2022 May 11;14(10):2371. doi: 10.3390/cancers14102371. Cancers (Basel). 2022. PMID: 35625975 Free PMC article. Review.
References
-
- Hart A, Smith JM, Skeans MA, et al. OPTN/SRTR 2018 annual data report: kidney. Am J Transplant . 2020;20(suppl s1):20–130.
-
- Chandrashekara S. The treatment strategies of autoimmune disease may need a different approach from conventional protocol: a review. Indian J Pharmacol . 2012;44(6):665–671.
-
- Vivier E, Raulet DH, Moretta A, et al. Innate or adaptive immunity? The example of natural killer cells. Science . 2011;331(6013):44–49.
-
- Fauci AS, Dale DC, Balow JE. Glucocorticosteroid therapy: mechanisms of action and clinical considerations. Ann Intern Med . 1976;84(3):304–315.
-
- Marx J. How the glucocorticoids suppress immunity. Science . 1995;270(5234):232–233.
MeSH terms
LinkOut - more resources
Full Text Sources
Medical