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. 2022:2407:205-213.
doi: 10.1007/978-1-0716-1871-4_15.

Decidua Basalis: An Ex Vivo Model to Study HIV-1 Infection During Pregnancy and Beyond

Nabila Jabrane-Ferrat  1 , Hicham El Costa  2
Affiliations

Decidua Basalis: An Ex Vivo Model to Study HIV-1 Infection During Pregnancy and Beyond

Nabila Jabrane-Ferrat et al. Methods Mol Biol. 2022.

Abstract

The human decidua basalis, main uterine mucosa during pregnancy, provides an ex vivo model for studying natural protection of macrophages against HIV-1 infection at the mucosal level. Beyond pregnancy, the decidua constitutes also a valuable tool to assess tissue-resident macrophage infection. Here, we provide a detailed protocol for decidual macrophage purification and tissue infection.

Keywords: Decidua basalis; Decidual Macrophages (dM); Human Immunodeficiency Virus-1 (HIV-1); Infection; Pregnancy.

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References

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