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Review
. 2022 Jan 1;38(1):28-33.
doi: 10.1097/PEC.0000000000002599.

Ketofol for Procedural Sedation and Analgesia in the Pediatric Population

Ammarah U Iqbal  1 , Megan E Shuster  1 , Carl R Baum
Affiliations
Review

Ketofol for Procedural Sedation and Analgesia in the Pediatric Population

Ammarah U Iqbal et al. Pediatr Emerg Care. .

Abstract

The combination of ketamine and propofol, commonly referred to as ketofol, is sometimes used for procedural sedation and analgesia in the pediatric emergency department. This article reviews the pharmacology, dosing, and indications, as well as adverse effects and contraindications of ketamine, propofol, and ketofol.

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References

    1. Practice Guidelines for Moderate Procedural Sedation and Analgesia 2018: A Report by the American Society of Anesthesiologists Task Force on Moderate Procedural Sedation and Analgesia, the American Association of Oral and Maxillofacial Surgeons, American College of Radiology, American Dental Association, American Society of Dentist Anesthesiologists, and Society of Interventional Radiology. Anesthesiology . 2018;128:437–479.
    1. Khurmi N, Patel P, Kraus M, et al. Pharmacologic considerations for pediatric sedation and anesthesia outside the operating room: a review for anesthesia and non-anesthesia providers. Paediatr Drugs . 2017;19:435–446.
    1. Ketamine [package insert] . Lake Forest, IL: Hospira, Inc; 2021.
    1. Propofol [package insert] . Princeton, NJ: Dr Reddy's Laboratory, Inc; 2017.
    1. Amornyotin S. Ketofol: a combination of ketamine and propofol. J Anesth Crit Care Open Access . 2014;1:00031.

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