Published Erratum
doi: 10.1038/s41588-021-00998-6.
Author Correction: Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice
Lin Wang #
1
2
, Dominik Aschenbrenner #
3
4
, Zhiyang Zeng #
5
, Xiya Cao
5
, Daniel Mayr
6
7
8
, Meera Mehta
2
9
, Melania Capitani
3
4
, Neil Warner
2
, Jie Pan
2
9
, Liren Wang
10
11
, Qi Li
2
9
, Tao Zuo
12
13
, Sarit Cohen-Kedar
14
15
, Jiawei Lu
10
11
, Rico Chandra Ardy
6
7
8
, Daniel J Mulder
2
, Dilan Dissanayake
16
, Kaiyue Peng
1
, Zhiheng Huang
1
, Xiaoqin Li
17
, Yuesheng Wang
17
, Xiaobing Wang
18
, Shuchao Li
19
, Samuel Bullers
3
4
20
, Anís N Gammage
3
20
, Klaus Warnatz
21
22
, Ana-Iris Schiefer
23
, Gergely Krivan
24
, Vera Goda
24
, Walter H A Kahr
9
25
26
, Mathieu Lemaire
9
26
27
; Genomics England Research Consortium; Chien-Yi Lu
9
, Iram Siddiqui
28
, Michael G Surette
29
, Daniel Kotlarz
30
, Karin R Engelhardt
31
, Helen R Griffin
31
, Robert Rottapel
32
33
34
, Hélène Decaluwe
35
36
, Ronald M Laxer
16
37
, Michele Proietti
38
, Sophie Hambleton
39
, Suzanne Elcombe
40
, Cong-Hui Guo
2
9
, Bodo Grimbacher
38
41
42
43
, Iris Dotan
15
44
, Siew C Ng
12
13
, Spencer A Freeman
9
26
, Scott B Snapper
45
46
47
, Christoph Klein
30
, Kaan Boztug #
6
7
8
48
, Ying Huang #
49
, Dali Li #
50
, Holm H Uhlig #
3
4
, Aleixo M Muise #
51
52
53
54
55
Collaborators,
Affiliations
Collaborators
- Genomics England Research Consortium:
Affiliations
- 1 Department of Gastroenterology, Pediatric Inflammatory Bowel Disease Research Center, Children's Hospital of Fudan University, Shanghai, China.
- 2 SickKids Inflammatory Bowel Disease Center, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada.
- 3 Translational Gastroenterology Unit and Biomedical Research Centre, Nuffield Department of Clinical Medicine, Experimental Medicine Division, University of Oxford, Oxford, UK.
- 4 Department of Pediatrics, John Radcliffe Hospital, Oxford, UK.
- 5 Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China.
- 6 Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, Vienna, Austria.
- 7 CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
- 8 St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria.
- 9 Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada.
- 10 Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, East China Normal University, Shanghai, China.
- 11 School of Life Sciences, East China Normal University, Shanghai, China.
- 12 Center for Gut Microbiota Research, The Chinese University of Hong Kong, Hong Kong, China.
- 13 Institute of Digestive Disease, Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong, Hong Kong, China.
- 14 Felsenstein Medical Research Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
- 15 Division of Gastroenterology, Rabin Medical Center, Petah Tikva, Israel.
- 16 Division of Rheumatology, Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
- 17 Department of Gastroenterology, Zhengzhou Children's Hospital, Zhengzhou, China.
- 18 Neonate Department, Sanmenxia Central Hospital, Sanmenxia, China.
- 19 Department of Pediatrics, Lushi County Renmin Hospital, Sanmenxia, China.
- 20 Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
- 21 Department of Rheumatology and Clinical Immunology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
- 22 Center for Chronic Immunodeficiency (CCI), Medical Center, University of Freiburg, Freiburg, Germany.
- 23 Department of Clinical Pathology, Medical University Vienna, Vienna, Austria.
- 24 National Institute of Hematology and Infectious Diseases, Department for Pediatric Hematology and Hemopoietic Stem Cell Transplantation, Central Hospital of Southern Pest, Budapest, Hungary.
- 25 Division of Haematology/Oncology, Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
- 26 Cell Biology Program, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada.
- 27 Division of Nephrology, Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
- 28 Division of Pathology, Department of Pediatric Laboratory Medicine, University of Toronto, Toronto, Ontario, Canada.
- 29 Department of Medicine, Farncombe Family Digestion Health Institute, McMaster University, Hamilton, Ontario, Canada.
- 30 Department of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital, Ludwig Maximilian University Munich, Munich, Germany.
- 31 Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
- 32 Princess Margaret Cancer Centre, University Health Network, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
- 33 Department of Immunology, University of Toronto, Toronto, Ontario, Canada.
- 34 Division of Rheumatology, St. Michael's Hospital, Toronto, Ontario, Canada.
- 35 Division of Immunology and Rheumatology, Department of Pediatrics, Sainte-Justine University Hospital, Montreal, Quebec, Canada.
- 36 Cytokine and Adaptive Immunity Laboratory, Sainte-Justine University Hospital Research Center, Université de Montréal, Montreal, Quebec, Canada.
- 37 Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
- 38 Institute for Immunodeficiency, Center for Chronic Immunodeficiency (CCI), Medical Center, Faculty of Medicine, Albert-Ludwigs-University of Freiburg, Freiburg, Germany.
- 39 Faculty of Medical Sciences, 100KGP England, Newcastle University, Newcastle upon Tyne, UK.
- 40 Department of Immunology, Royal Victoria Infirmary, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
- 41 DZIF - German Center for Infection Research, Satellite Center Freiburg, Albert-Ludwigs-University of Freiburg, Freiburg, Germany.
- 42 CIBSS - Centre for Integrative Biological Signalling Studies, Albert-Ludwigs-University of Freiburg, Freiburg, Germany.
- 43 RESIST - Cluster of Excellence 2155 to Hanover Medical School, Satellite Center Freiburg, Albert-Ludwigs-University of Freiburg, Freiburg, Germany.
- 44 Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
- 45 Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA.
- 46 Harvard Medical School, Boston, MA, USA.
- 47 Division of Gastroenterology, Brigham and Women's Hospital, Boston, MA, USA.
- 48 St. Anna Children's Hospital, Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.
- 49 Department of Gastroenterology, Pediatric Inflammatory Bowel Disease Research Center, Children's Hospital of Fudan University, Shanghai, China. yhuang815@163.com.
- 50 Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China. dlli@bio.ecnu.edu.cn.
- 51 SickKids Inflammatory Bowel Disease Center, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada. aleixo.muise@utoronto.ca.
- 52 Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada. aleixo.muise@utoronto.ca.
- 53 Cell Biology Program, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada. aleixo.muise@utoronto.ca.
- 54 Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada. aleixo.muise@utoronto.ca.
- 55 Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada. aleixo.muise@utoronto.ca.
# Contributed equally.
- PMID: 34987219
- DOI: 10.1038/s41588-021-00998-6
Item in Clipboard
Published Erratum
Author Correction: Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice
Lin Wang et al.
Nat Genet.
2022 Feb.
Display options
Format
doi: 10.1038/s41588-021-00998-6.
Authors
Lin Wang #
1
2
, Dominik Aschenbrenner #
3
4
, Zhiyang Zeng #
5
, Xiya Cao
5
, Daniel Mayr
6
7
8
, Meera Mehta
2
9
, Melania Capitani
3
4
, Neil Warner
2
, Jie Pan
2
9
, Liren Wang
10
11
, Qi Li
2
9
, Tao Zuo
12
13
, Sarit Cohen-Kedar
14
15
, Jiawei Lu
10
11
, Rico Chandra Ardy
6
7
8
, Daniel J Mulder
2
, Dilan Dissanayake
16
, Kaiyue Peng
1
, Zhiheng Huang
1
, Xiaoqin Li
17
, Yuesheng Wang
17
, Xiaobing Wang
18
, Shuchao Li
19
, Samuel Bullers
3
4
20
, Anís N Gammage
3
20
, Klaus Warnatz
21
22
, Ana-Iris Schiefer
23
, Gergely Krivan
24
, Vera Goda
24
, Walter H A Kahr
9
25
26
, Mathieu Lemaire
9
26
27
; Genomics England Research Consortium; Chien-Yi Lu
9
, Iram Siddiqui
28
, Michael G Surette
29
, Daniel Kotlarz
30
, Karin R Engelhardt
31
, Helen R Griffin
31
, Robert Rottapel
32
33
34
, Hélène Decaluwe
35
36
, Ronald M Laxer
16
37
, Michele Proietti
38
, Sophie Hambleton
39
, Suzanne Elcombe
40
, Cong-Hui Guo
2
9
, Bodo Grimbacher
38
41
42
43
, Iris Dotan
15
44
, Siew C Ng
12
13
, Spencer A Freeman
9
26
, Scott B Snapper
45
46
47
, Christoph Klein
30
, Kaan Boztug #
6
7
8
48
, Ying Huang #
49
, Dali Li #
50
, Holm H Uhlig #
3
4
, Aleixo M Muise #
51
52
53
54
55
Collaborators
- Genomics England Research Consortium:
Affiliations
- 1 Department of Gastroenterology, Pediatric Inflammatory Bowel Disease Research Center, Children's Hospital of Fudan University, Shanghai, China.
- 2 SickKids Inflammatory Bowel Disease Center, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada.
- 3 Translational Gastroenterology Unit and Biomedical Research Centre, Nuffield Department of Clinical Medicine, Experimental Medicine Division, University of Oxford, Oxford, UK.
- 4 Department of Pediatrics, John Radcliffe Hospital, Oxford, UK.
- 5 Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China.
- 6 Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, Vienna, Austria.
- 7 CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
- 8 St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria.
- 9 Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada.
- 10 Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, East China Normal University, Shanghai, China.
- 11 School of Life Sciences, East China Normal University, Shanghai, China.
- 12 Center for Gut Microbiota Research, The Chinese University of Hong Kong, Hong Kong, China.
- 13 Institute of Digestive Disease, Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong, Hong Kong, China.
- 14 Felsenstein Medical Research Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
- 15 Division of Gastroenterology, Rabin Medical Center, Petah Tikva, Israel.
- 16 Division of Rheumatology, Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
- 17 Department of Gastroenterology, Zhengzhou Children's Hospital, Zhengzhou, China.
- 18 Neonate Department, Sanmenxia Central Hospital, Sanmenxia, China.
- 19 Department of Pediatrics, Lushi County Renmin Hospital, Sanmenxia, China.
- 20 Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
- 21 Department of Rheumatology and Clinical Immunology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
- 22 Center for Chronic Immunodeficiency (CCI), Medical Center, University of Freiburg, Freiburg, Germany.
- 23 Department of Clinical Pathology, Medical University Vienna, Vienna, Austria.
- 24 National Institute of Hematology and Infectious Diseases, Department for Pediatric Hematology and Hemopoietic Stem Cell Transplantation, Central Hospital of Southern Pest, Budapest, Hungary.
- 25 Division of Haematology/Oncology, Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
- 26 Cell Biology Program, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada.
- 27 Division of Nephrology, Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
- 28 Division of Pathology, Department of Pediatric Laboratory Medicine, University of Toronto, Toronto, Ontario, Canada.
- 29 Department of Medicine, Farncombe Family Digestion Health Institute, McMaster University, Hamilton, Ontario, Canada.
- 30 Department of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital, Ludwig Maximilian University Munich, Munich, Germany.
- 31 Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
- 32 Princess Margaret Cancer Centre, University Health Network, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
- 33 Department of Immunology, University of Toronto, Toronto, Ontario, Canada.
- 34 Division of Rheumatology, St. Michael's Hospital, Toronto, Ontario, Canada.
- 35 Division of Immunology and Rheumatology, Department of Pediatrics, Sainte-Justine University Hospital, Montreal, Quebec, Canada.
- 36 Cytokine and Adaptive Immunity Laboratory, Sainte-Justine University Hospital Research Center, Université de Montréal, Montreal, Quebec, Canada.
- 37 Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
- 38 Institute for Immunodeficiency, Center for Chronic Immunodeficiency (CCI), Medical Center, Faculty of Medicine, Albert-Ludwigs-University of Freiburg, Freiburg, Germany.
- 39 Faculty of Medical Sciences, 100KGP England, Newcastle University, Newcastle upon Tyne, UK.
- 40 Department of Immunology, Royal Victoria Infirmary, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
- 41 DZIF - German Center for Infection Research, Satellite Center Freiburg, Albert-Ludwigs-University of Freiburg, Freiburg, Germany.
- 42 CIBSS - Centre for Integrative Biological Signalling Studies, Albert-Ludwigs-University of Freiburg, Freiburg, Germany.
- 43 RESIST - Cluster of Excellence 2155 to Hanover Medical School, Satellite Center Freiburg, Albert-Ludwigs-University of Freiburg, Freiburg, Germany.
- 44 Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
- 45 Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA.
- 46 Harvard Medical School, Boston, MA, USA.
- 47 Division of Gastroenterology, Brigham and Women's Hospital, Boston, MA, USA.
- 48 St. Anna Children's Hospital, Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.
- 49 Department of Gastroenterology, Pediatric Inflammatory Bowel Disease Research Center, Children's Hospital of Fudan University, Shanghai, China. yhuang815@163.com.
- 50 Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China. dlli@bio.ecnu.edu.cn.
- 51 SickKids Inflammatory Bowel Disease Center, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada. aleixo.muise@utoronto.ca.
- 52 Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada. aleixo.muise@utoronto.ca.
- 53 Cell Biology Program, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada. aleixo.muise@utoronto.ca.
- 54 Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada. aleixo.muise@utoronto.ca.
- 55 Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada. aleixo.muise@utoronto.ca.
# Contributed equally.
- PMID: 34987219
- DOI: 10.1038/s41588-021-00998-6
Item in Clipboard
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No abstract available
Erratum for
-
Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice.Wang L, Aschenbrenner D, Zeng Z, Cao X, Mayr D, Mehta M, Capitani M, Warner N, Pan J, Wang L, Li Q, Zuo T, Cohen-Kedar S, Lu J, Ardy RC, Mulder DJ, Dissanayake D, Peng K, Huang Z, Li X, Wang Y, Wang X, Li S, Bullers S, Gammage AN, Warnatz K, Schiefer AI, Krivan G, Goda V, Kahr WHA, Lemaire M; Genomics England Research Consortium; Lu CY, Siddiqui I, Surette MG, Kotlarz D, Engelhardt KR, Griffin HR, Rottapel R, Decaluwe H, Laxer RM, Proietti M, Hambleton S, Elcombe S, Guo CH, Grimbacher B, Dotan I, Ng SC, Freeman SA, Snapper SB, Klein C, Boztug K, Huang Y, Li D, Uhlig HH, Muise AM. Wang L, et al. Nat Genet. 2021 Apr;53(4):500-510. doi: 10.1038/s41588-021-00803-4. Epub 2021 Mar 29. Nat Genet. 2021. PMID: 33782605 Free PMC article.
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