Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2022 Mar;18(3):129-130.
doi: 10.1038/s41582-021-00613-6.

Schizophrenia: genetic insights with clinical potential

Affiliations
Comment

Schizophrenia: genetic insights with clinical potential

Olav B Smeland et al. Nat Rev Neurol. 2022 Mar.
No abstract available

PubMed Disclaimer

Comment on

References

    1. Charlson, F. J. et al. Global epidemiology and burden of schizophrenia: findings from the Global Burden of Disease Study 2016. Schizophr. Bull. 44, 1195–1203 (2018). - DOI
    1. Smeland, O. B., Frei, O., Dale, A. M. & Andreassen, O. A. The polygenic architecture of schizophrenia — rethinking pathogenesis and nosology. Nat. Rev. Neurol. 16, 366–379 (2020). - DOI
    1. The Schizophrenia Working Group of the Psychiatric Genomics Consortium. Mapping genomic loci prioritises genes and implicates synaptic biology in schizophrenia. Preprint at https://www.medrxiv.org/content/10.1101/2020.09.12.20192922v1 (2020).
    1. Singh, T., Neale, B. M. & Daly, M. J. Exome sequencing identifies rare coding variants in 10 genes which confer substantial risk for schizophrenia. Preprint at https://www.medrxiv.org/content/10.1101/2020.09.18.20192815v1 (2020).
    1. Smeland, O. B. & Andreassen, O. A. Polygenic risk scores in psychiatry – large potential but still limited clinical utility. Eur. Neuropsychopharmacol. 51, 68–70 (2021). - DOI

LinkOut - more resources