Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Mar 1;17(5):e202101315.
doi: 10.1002/asia.202101315. Epub 2022 Jan 22.

Recent Advances in Constructing Higher-Order DNA Structures

Jing Wang  1   2 , Dong-Xia Wang  1 , Bo Liu  1 , Xiao Jing  1 , Dan-Ye Chen  1 , An-Na Tang  1 , Yun-Xi Cui  3 , De-Ming Kong  1
Affiliations
Review

Recent Advances in Constructing Higher-Order DNA Structures

Jing Wang et al. Chem Asian J. .

Abstract

Molecular self-assembly is widely used in the fields of biosensors, molecular devices, efficient catalytic materials, and medical biomaterials. As the carrier of genetic information, DNA is a kind of biomacromolecule composed of deoxyribonucleotide units. DNA nanotechnology extends DNA of its original properties as a molecule that stores and transmits genetic information from its biological environment by taking advantage of its unique base pairing and inherent biocompatibility to produce structurally-defined supramolecular structures. With the continuously development of DNA technology, the assembly method of DNA nanostructures is not only limited on the basis of DNA hybridization but also other biochemical interactions. In this review, we summarize the latest methods used to construct higher-order DNA structures. The problems of DNA nanostructures are discussed and the future directions in this field are provided.

Keywords: DNA nanostructures; DNA nanotechnology; DNA-based materials; higher-order; self-assembly.

PubMed Disclaimer

References

    1. None
    1. W. Pfeifer, B. Saccà, ChemBioChem 2016, 17, 1063-1080;
    1. C. Lin, Y. Liu, S. Rinker, H. Yan, ChemPhysChem 2006, 7, 1641-1647.
    1. None
    1. Y. Hu, Y. Wang, J. Yan, N. Wen, H. Xiong, S. Cai, Q. He, D. Peng, Z. Liu, Y. Liu, Adv. Sci. (Weinh) 2020, 7, 2000557;

LinkOut - more resources