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Editorial
. 2022 Jan 6;139(1):12-13.
doi: 10.1182/blood.2021014466.

COVID-specific T's may offset therapeutically endangered B's

LaQuisa C Hill  1 , Premal D Lulla  1
Affiliations
Editorial

COVID-specific T's may offset therapeutically endangered B's

LaQuisa C Hill et al. Blood. .
No abstract available

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Figures

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When compared with healthy individuals (A), Liebers et al and Enßle et al in this issue of Blood demonstrate that myeloma and lymphoma patients (B) have reduced total numbers and function of T cells and even fewer B cells to mount an immune response to COVID-19 vaccination. mRNA, messenger RNA. Illustration by Walter Mejia.
See this image and copyright information in PMC

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References

    1. Liebers N, Speer C, Benning L, et al. Humoral and cellular responses after COVID-19 vaccination in anti-CD20 treated lymphoma patients [letter] Blood. 2022;139(1):137–142. - PMC - PubMed
    1. Enßle JC, Campe J, Schwenger A, et al. Severe impairment of T-cell responses to BNT162b2 immunization in patients with multiple myeloma [letter] Blood. 2021;139(1):141–145. - PMC - PubMed
    1. Stephenson KE, Le Gars M, Sadoff J, et al. Immunogenicity of the Ad26.COV2.S vaccine for COVID-19. JAMA. 2021;325(15):1535–1544. - PMC - PubMed
    1. Walsh EE, Frenck RW, Jr, Falsey AR, et al. Safety and immunogenicity of two RNA-based Covid-19 vaccine candidates. N Engl J Med. 2020;383(25):2439–2450. - PMC - PubMed
    1. Sahin U, Muik A, Vogler I, et al. BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans. Nature. 2021;595(7868):572–577. - PubMed

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