T cells to fix a broken heart

Torahito A Gao¹, Yvonne Y Chen^{1

2

3}

Affiliations

¹ Department of Chemical and Biomolecular Engineering, University of California, Los Angeles (UCLA), Los Angeles, CA, USA.
² Department of Microbiology, Immunology, and Molecular Genetics, UCLA, Los Angeles, CA, USA.
³ Parker Institute for Cancer Immunotherapy Center at UCLA, Los Angeles, CA, USA.

Comment

Torahito A Gao et al. Science. 2022.

. 2022 Jan 7;375(6576):23-24.

doi: 10.1126/science.abn0851. Epub 2022 Jan 6.

Torahito A Gao¹, Yvonne Y Chen^{1

2

3}

¹ Department of Chemical and Biomolecular Engineering, University of California, Los Angeles (UCLA), Los Angeles, CA, USA.
² Department of Microbiology, Immunology, and Molecular Genetics, UCLA, Los Angeles, CA, USA.
³ Parker Institute for Cancer Immunotherapy Center at UCLA, Los Angeles, CA, USA.

Abstract

In vivo engineered T cells provide a promising approach to treat cardiac diseases.

CAR T cells produced in vivo to treat cardiac injury.
Rurik JG, Tombácz I, Yadegari A, Méndez Fernández PO, Shewale SV, Li L, Kimura T, Soliman OY, Papp TE, Tam YK, Mui BL, Albelda SM, Puré E, June CH, Aghajanian H, Weissman D, Parhiz H, Epstein JA. Rurik JG, et al. Science. 2022 Jan 7;375(6576):91-96. doi: 10.1126/science.abm0594. Epub 2022 Jan 6. Science. 2022. PMID: 34990237 Free PMC article.