Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Dec 20:12:621.
doi: 10.25259/SNI_946_2021. eCollection 2021.

Intracranial arachnoid cysts: Review of natural history and proposed treatment algorithm

Affiliations
Review

Intracranial arachnoid cysts: Review of natural history and proposed treatment algorithm

John Carbone et al. Surg Neurol Int. .

Abstract

Background: With a prevalence of 1.4%, intracranial arachnoid cysts are a frequent incidental finding on MRI and CT. Whilst most cysts are benign in the long-term, clinical practice, and imaging frequency does not necessarily reflect this.

Methods: A literature review was conducted searching the Medline database with MESH terms. This literature was condensed into an article, edited by a consultant neurosurgeon. This was further condensed, presented to the neurosurgery department at Princess Alexandra Hospital for final feedback and editing.

Results: This review advises that asymptomatic patients with typical cysts have a low risk of cyst growth and development of new symptomatology, thus do not require surveillance or intervention. The minority of symptomatic patients or those with cysts in sensitive areas may require referral to a neurosurgeon for clinical follow-up or intervention.

Conclusion: Greater than 94% of patients are asymptomatic, practitioners can be confident in reassuring patients of the benign nature of a potentially worrying finding. Recognizing the small number of symptomatic patients and those with cysts in areas sensitive to causing hydrocephalus is where GP decision making in conjunction with specialty input is of highest yield.

Keywords: Arachnoid cyst; Communication; General practice; Neurosurgery; Treatment algorithm.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1:
Figure 1:
Treatment algorithm for patients presenting with an arachnoid cyst.

References

    1. Al-Holou WN, Terman S, Kilburg C, Garton HJ, Muraszko KM, Maher CO. Prevalence and natural history of arachnoid cysts in adults. J Neurosurg. 2013;118:222–31. - PubMed
    1. Basaldella L, Orvieto E, Dei Tos AP, Della Barbera M, Valente M, Longatti P. Causes of arachnoid cyst development and expansion. Neurosurg Focus. 2007;22:E4. - PubMed
    1. Berle M, Wester KG, Ulvik RJ, Kroksveen AC, Haaland OA, Amiry-Moghaddam M, et al. Arachnoid cysts do not contain cerebrospinal fluid: A comparative chemical analysis of arachnoid cyst fluid and cerebrospinal fluid in adults. Cerebrospinal Fluid Res. 2010;7:8. - PMC - PubMed
    1. Chen Y, Fang HJ, Li ZF, Yu SY, Li CZ, Wu ZB, et al. Treatment of middle cranial fossa arachnoid cysts: A systematic review and meta-analysis. World Neurosurg. 2016;92:480–90.e2. - PubMed
    1. Cinalli G, Spennato P, Columbano L, Ruggiero C, Aliberti F, Trischitta V, et al. Neuroendoscopic treatment of arachnoid cysts of the quadrigeminal cistern: A series of 14 cases. J Neurosurg Pediatr. 2010;6:489–97. - PubMed

LinkOut - more resources