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. 2022 Jan;12(1):862-867.
doi: 10.21037/qims-20-1319.

Unexpected discovery of prostatic diffuse large B-cell lymphoma after thulium laser vaporization in a patient with Waldenstrom macroglobulinemia

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Unexpected discovery of prostatic diffuse large B-cell lymphoma after thulium laser vaporization in a patient with Waldenstrom macroglobulinemia

Jialei Wang et al. Quant Imaging Med Surg. 2022 Jan.
No abstract available

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Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://dx.doi.org/10.21037/qims-20-1319). The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Images from 18F-FDG PET/CT for the WM patient. The images show abnormal tracer uptake of the prostate (SUVmax 27.0). Abnormal focal tracer accumulations in the left pulmonary nodule, and the mediastinal, retroperitoneal, and pelvic lymph nodes are also apparent. (A) MIP; (B-D) PET; (E-G) CT; (H-J) fused PET/CT. The prostatic lesion is indicated by the arrow. MIP, maximal intensity projection; PET, positron emission tomography; CT, computed tomography; WM, Waldenstrom macroglobulinemia; SUV, standardized uptake value.
Figure 2
Figure 2
Prostate MRI images at 1 month after ThuVAP of the prostate. The images show locally enlarged prostate mass, measuring up to 107 mm × 104 mm × 179 mm. The rectum was obviously compressed by the mass, which led to defecation difficulty in this case. The MRI report concluded that the mass was prostate carcinoma. The final biopsy histology was DLBCL of the prostate. (A-C) T2WI shows an equal signal; (D) DWI shows restricted diffusion with b value of 800 s/mm2. (A) Axial view; (B) sagittal view; (C) coronal view; (D) DWI view. The prostatic lesion is marked by an asterisk. DWI, diffusion-weighted imaging; MRI, magnetic resonance imaging; ThuVAP, thulium vaporization; DLBCL, diffuse large B-cell lymphoma; T2WI, T2 weighted imaging.

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References

    1. Jiménez C, Alonso-Álvarez S, Alcoceba M, Ordóñez GR, García-Álvarez M, Prieto-Conde MI, Chillón MC, Balanzategui A, Corral R, Marín LA, Gutiérrez NC, Puig N, Sarasquete ME, González M, García-Sanz R. From Waldenström's macroglobulinemia to aggressive diffuse large B-cell lymphoma: a whole-exome analysis of abnormalities leading to transformation. Blood Cancer J 2017;7:e591. 10.1038/bcj.2017.72 - DOI - PMC - PubMed
    1. Shakeri A, Kaffenberger BH, Gru AA. Cutaneous macroglobulinosis as the initial presentation of Waldenström macroglobulinemia in a patient with a history of diffuse large B-cell lymphoma. J Cutan Pathol 2018;45:962-4. 10.1111/cup.13335 - DOI - PubMed
    1. Treon SP, Xu L, Yang G, Zhou Y, Liu X, Cao Y, Sheehy P, Manning RJ, Patterson CJ, Tripsas C, Arcaini L, Pinkus GS, Rodig SJ, Sohani AR, Harris NL, Laramie JM, Skifter DA, Lincoln SE, Hunter ZR. MYD88 L265P somatic mutation in Waldenström's macroglobulinemia. N Engl J Med 2012;367:826-33. 10.1056/NEJMoa1200710 - DOI - PubMed
    1. Yu X, Li W, Deng Q, Li L, Hsi ED, Young KH, Zhang M, Li Y. MYD88 L265P Mutation in Lymphoid Malignancies. Cancer Res 2018;78:2457-62. 10.1158/0008-5472.CAN-18-0215 - DOI - PubMed
    1. Warrick JI, Owens SR, Tomlins SA. Diffuse large B-cell lymphoma of the prostate. Arch Pathol Lab Med 2014;138:1286-9. 10.5858/arpa.2014-0276-CC - DOI - PubMed