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Review
. 2022 Jan 20;386(3):264-272.
doi: 10.1056/NEJMcp2117115. Epub 2022 Jan 7.

Rapid Diagnostic Testing for SARS-CoV-2

Paul K Drain  1
Affiliations
Review

Rapid Diagnostic Testing for SARS-CoV-2

Paul K Drain. N Engl J Med. .
No abstract available

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Figures

Figure 1
Figure 1. Pathophysiology and Timeline of Viremia, Antigenemia, and Immune Response during Acute SARS-CoV-2 Infection.
In some persons, reverse-transcriptase–polymerase-chain-reaction (RT-PCR) tests can remain positive for weeks or months after initial infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but this positivity rarely indicates replication-competent virus that can result in infection.
Figure 2
Figure 2. Indications and Algorithms for Rapid Diagnostic Tests (RDTs) for SARS-CoV-2.
The Centers for Disease Control and Prevention defines a close contact as a person who was less than 6 feet away for 15 minutes or more over a 24-hour period., Potential high-risk transmission settings include an airplane, a concert or sporting event, and a crowded or poorly ventilated indoor area.,, Covid-19 denotes coronavirus disease 2019.
See this image and copyright information in PMC

Comment in

  • Rapid Diagnostic Testing for SARS-CoV-2.
    Bogaty P. Bogaty P. N Engl J Med. 2022 Apr 28;386(17):e47. doi: 10.1056/NEJMc2202308. Epub 2022 Apr 13. N Engl J Med. 2022. PMID: 35417629 No abstract available.
  • Update on rapid diagnostic testing for SARS-CoV-2.
    Dugerdil A, Flahault A. Dugerdil A, et al. Anaesth Crit Care Pain Med. 2022 Aug;41(4):101114. doi: 10.1016/j.accpm.2022.101114. Epub 2022 Jun 16. Anaesth Crit Care Pain Med. 2022. PMID: 35718330 Free PMC article. No abstract available.

References

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    1. Technical specifications for selection of essential in vitro diagnostics for SARS-CoV-2. Geneva: World Health Organization, April 19, 2021. (https://www.who.int/publications/m/item/technical-specifications-for-sel...).
    1. Ritchie H, Mathieu E, Rodés-Guirao L, et al. Coronavirus pandemic (COVID-19). Our World in Data (https://ourworldindata.org/coronavirus).
    1. Wu SL, Mertens AN, Crider YS, et al. Substantial underestimation of SARS-CoV-2 infection in the United States. Nat Commun 2020;11:4507-4507. - PMC - PubMed
    1. Institute for Health Metrics and Evaluation. COVID-19 has caused 6.9 million deaths globally, more than double what official reports show. May 6, 2021. (http://www.healthdata.org/news-release/covid-19-has-caused-69-million-de...).