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Comment
. 2022 Jan 6;29(1):3-4.
doi: 10.1016/j.stem.2021.12.003.

Enteric glia bring fresh WNT to the intestinal stem cell niche

Fränze Progatzky  1 , Vassilis Pachnis  2
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Enteric glia bring fresh WNT to the intestinal stem cell niche

Fränze Progatzky et al. Cell Stem Cell. .
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Abstract

Intestinal stem cells continuously self-renew and differentiate into a variety of specialized epithelial cells that maintain gut health. New research in this issue of Cell Stem Cell (Baghdadi et al., 2022) shows that enteric glial cells regulate the intestinal stem cell niche during regeneration and disease through the production of WNT ligands.

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