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Case Reports
. 2022 Mar-Apr;97(2):231-235.
doi: 10.1016/j.abd.2020.09.016. Epub 2022 Jan 4.

Necrotic erythema nodosum reaction associated with histological alterations of Lucio's phenomenon

Affiliations
Case Reports

Necrotic erythema nodosum reaction associated with histological alterations of Lucio's phenomenon

Larissa Daniele Machado Góes et al. An Bras Dermatol. 2022 Mar-Apr.

Abstract

Patients with lepromatous or borderline leprosy may present two types of vasculonecrotic reactions: Lucio's phenomenon (LP) and necrotic erythema nodosum leprosum (nENL). These are serious conditions, which mostly lead to life-threatening infectious and thrombotic complications. The authors report the case of a patient with leprosy recurrence associated with an atypical type II reaction with LP characteristics on histopathology.

Keywords: Leprosy; Multibacillary leprosy; Mycobacterium infections; Mycobacterium leprae.

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Figures

Figure 1
Figure 1
Presence of papules, pustules and crusts on the upper limbs and trunk.
Figure 2
Figure 2
(A), Erythematous papules, pustules and crusts affecting the left upper limb. (B), Bullae with purulent content on the left plantar region.
Figure 3
Figure 3
(A), Necrosis of the epidermis and dense inflammatory infiltrate in the dermis are observed (Hematoxylin & eosin, ×10). (B), Neutrophilic infiltrate on the wall and around the vessels (Hematoxylin & eosin, ×40). (C), Vacuolated macrophages containing large amounts of intact and fragmented bacilli (Wade, ×40).

References

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