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. 2022 Mar;41(3):505-509.
doi: 10.1007/s10096-021-04393-1. Epub 2022 Jan 9.

Minimal prevalence of HPV vaccination and common occurrence of high-risk HPV types in pregnant women with HIV: data from a national study in Italy

Marco Floridia  1 , Giulia Masuelli  2 , Beatrice Tassis  3 , Valeria M Savasi  4 , Matilde Sansone  5 , Arsenio Spinillo  6 , Laura Franceschetti  7 , Giovanni Guaraldi  8 , Carmela Pinnetti  9 , Serena Dalzero  10 , Alessandra Meloni  11 , Antonella Vimercati  12 , Giuliana Simonazzi  13 , Enrica Tamburrini  14 , Marina Ravizza  10 ; Italian Group on Surveillance of Antiretroviral Treatment in Pregnancy
Affiliations

Minimal prevalence of HPV vaccination and common occurrence of high-risk HPV types in pregnant women with HIV: data from a national study in Italy

Marco Floridia et al. Eur J Clin Microbiol Infect Dis. 2022 Mar.

Abstract

Among 733 pregnant women with HIV followed between 2013 and 2021, only 8 (1.1%) had prior HPV vaccination. One had low-grade squamous intraepithelial lesions [LSIL], and none had HPV type information. Among the 725 non-vaccinated women, 578 (79.7%) had information on cervical cytology. Rate of cytologic abnormalities in this group was 20.6% (0.2% atypical glandular cells of undetermined significance [AGC], 1.7% atypical squamous cells of undetermined significance [ASC-US], 11.1% LSIL, and 7.6% high-grade squamous intraepithelial lesions [HSIL]). Among 56 women with HPV type information, 75.0% carried high risk types, with similar occurrence in women with and without cytologic abnormalities, 30.4% had multiple high-risk types, and 75.9% carried at least one of the types included in the currently recommended 9-valent vaccine.

Keywords: Cervical HPV; Cervical cytology; HIV; HPV types; HPV vaccination; Women.

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