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. 2022 Apr;49(4):398-406.
doi: 10.1111/joor.13304. Epub 2022 Jan 17.

Oral health-related quality of life in patients with Parkinson's disease

Merel C Verhoeff  1 , Frank Lobbezoo  1 , Astrid M van Leeuwen  1 , Annemarie A Schuller  2   3 , Michail Koutris  1
Affiliations

Oral health-related quality of life in patients with Parkinson's disease

Merel C Verhoeff et al. J Oral Rehabil. 2022 Apr.

Abstract

Background: Parkinson's disease (PD) is a neurodegenerative condition affecting the quality of life. Due to a worsening of oral health in PD patients with the progression of the disease, oral health-related quality of life (OHRQoL) could be impaired as well.

Objectives: To assess whether PD patients in The Netherlands experience worse OHRQoL than historical controls, and to investigate which factors are associated with OHRQoL in PD patients.

Materials & methods: In total, 341 PD patients (65.5 ± 8.4 years) and 411 historical controls (62.6 ± 5.3 years) participated. Both groups completed a questionnaire. The PD patients were asked questions regarding demographics, PD, oral health, and OHRQoL. The historical controls filled in demographic information and questions regarding OHRQoL. The latter construct was assessed using the Dutch 14-item version of the Oral Health Impact Profile (OHIP-14). Data were analysed using independent samples t-tests and univariate and multivariate linear regression analysis.

Results: The mean OHIP-14 score was higher in PD patients (19.1 ± 6.7) than in historical controls (16.5 ± 4.4) (t(239) = 6.5; p < .001). OHRQoL in PD patients was statistically significant associated with motor aspects of experiences of daily living (B = 0.31; t(315) = 7.03; p < .001), worsening of the oral environment during disease course (B = 3.39; t(315) = 4.21; p < .001), being dentate (B = -5.60; t(315) = -4.5; p < .001), tooth wear (B = 2.25; t(315) = 3.29; p = .001), and possible burning mouth syndrome (B = 5.87; t(315) = 2.87; p = .004).

Conclusion: PD patients had a lower OHRQoL than historical controls. Besides, PD-related variables and oral health-related variables were associated with OHRQoL.

Keywords: Parkinson's disease; dental care for aged; oral health; quality of life; self-assessment; tooth wear.

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Conflict of interest statement

Dr. Lobbezoo reports Grants from Sunstar Suisse SA, Vivisol‐Resmed, Airway Management, Somnomed‐Goedegebuure, Health Holland/TKI, and membership Academic Advisory Board for GrindCare, outside the submitted work. Dr. Schuller reports grants from the National Health Care Institute (Zorginstituut Nederland), during the conduct of the study.

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