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. 2021 Nov 22:18:93.
doi: 10.4103/1735-3327.330874. eCollection 2021.

A randomized control trial comparing the efficacy of 3Mixtatin and Modified 3Mix-MP paste using lesion sterilization and tissue repair technique to conventional root canal treatment in primary molars of children aged 4-8 years: An in vivo study

Seema Thakur  1 , Aman Deep  1 , Parul Singhal  1 , Deepak Chauhan  1
Affiliations

A randomized control trial comparing the efficacy of 3Mixtatin and Modified 3Mix-MP paste using lesion sterilization and tissue repair technique to conventional root canal treatment in primary molars of children aged 4-8 years: An in vivo study

Seema Thakur et al. Dent Res J (Isfahan). .

Abstract

Background: The aim of this study was to evaluate clinical and radiographic success rates of 3Mixtatin and Modified 3Mix-MP paste and compare it with conventional root canal treatment procedure in primary molars requiring pulpectomy.

Materials and methods: In this in vivo study, 66 primary molars in 52 children aged between 4 and 8 years with primary molars having chronic periapical abscess were treated randomly with 3Mixtatin, Modified 3Mix-MP paste, and Metapex. The subjects were reviewed at 6 and 12 months both clinically and radiographically after pulpal therapy to evaluate and compare the healing process. The data obtained were subjected to statistical analysis at a significance level of 0.05.

Results: By the end of 12-month follow-up among the three groups, Group I seemed to be performing consistently better as compared to the other two groups when evaluated clinically and radiographically. However, Group III resulted in the greatest number of failures, with success rate being mere 42.9% at the end of follow-up period.

Conclusion: Radiographic and clinical healing occurred in all the three groups; however, based on our results, Group I seemed to be performing consistently better among the three groups at 12-month follow-up. Hence, it can be inferred that 3Mixtatin used as a localized agent is effective and comparable to both Modified 3Mix-MP paste and conventional pulpectomy procedure involving calcium hydroxide and iodoform paste in primary teeth.

Keywords: Metapex; primary teeth; pulpectomy.

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Conflict of interest statement

The authors of this manuscript declare that they have no conflicts of interest, real or perceived, financial or non-financial in this article.

Figures

Figure 1
Figure 1
Flow of participants undergoing various treatment modalities.
Figure 2
Figure 2
(a) Access opening in right maxillary second primary molar teeth, (b) Freshly Mixed 3Mixtatin paste, (c) Freshly Mixed Modified 3Mix-MP paste, (d) Triple antibiotic paste placed with in the pulp chamber, (e) Obturating the primary molar canals with prepacked syringe of calcium hydroxide and iodoform paste, (f) Restoration of primary molars with stainless steel crowns.
Figure 3
Figure 3
(a) Group I (3Mixtatin) preoperative radiograph, (b) Postoperative radiograph, (c) Radiograph at 6-month interval, (d) Radiograph at 12-month interval, (e) Group II (Modified 3Mix-MP paste) Preoperative Radiograph, (f) Postoperative Radiograph, (g) Radiograph at 6-month interval, (h) Radiograph at 12-month interval, (i) Group III (calcium hydroxide iodoform paste) preoperative radiograph, (j) Postoperative radiograph, (k) Radiograph at 6-month interval, (l) Radiograph at 12-month interval.
Figure 4
Figure 4
Depicts clinical success and failure among three groups at 6- and 12-month intervals.
Figure 5
Figure 5
Depicts radiological success and failure among three groups at 6- and 12-month intervals.
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