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. 2021 Jul-Sep;47(3):420-427.
doi: 10.12865/CHSJ.47.03.13. Epub 2021 Sep 30.

A Cross-Sectional Study to Assess Thyroid Function in Infants and Children in a City from South-Western Romania

Corina Maria Vasile  1   2 , Alice Elena Ghenea  3 , Anca Loredana Udriştoiu  4 , Ştefan Udriştoiu  4 , Mihaela Popescu  5 , Vlad Padureanu  6 , Dragoş Ovidiu Alexandru  7
Affiliations

A Cross-Sectional Study to Assess Thyroid Function in Infants and Children in a City from South-Western Romania

Corina Maria Vasile et al. Curr Health Sci J. 2021 Jul-Sep.

Abstract

Thyroid hormones are critical regulators of growth, myelination of the nervous system, metabolism, and organ function. The most prevalent endocrinopathies in childhood are related to thyroid disorders. Thyroid problems in children and adolescents have a significantly different etiology and clinical presentation than in adults. Thus, pediatric medical care involves an understanding of the unique features of thyroid function and dysfunction during childhood and adolescence. The etiology and clinical manifestations of thyroid disorders in children and adolescents are vastly different from those in adults. The particular aspects of thyroid function and malfunction in childhood and adolescence are hence part of pediatric medical therapy. To prevent persistent nervous system damage and developmental problems, it is vital to recognize and treat thyroid dysfunction in neonates as early as possible. The purpose of the research was to understand more how children's thyroid problems function, structure, and prevalence. The research examined 30 children under the age of 16 years who had symptoms that were linked to thyroid problems. In addition to demographic and family information, thyroid ultrasounds and blood samples for the detection of T3, T4, and TSH were obtained. Females surpassed males by a small majority (2.33:1 ratio).Out of the total children included in the study, 14(46.7%) cases for autoimmune thyroiditis, 2(6.67%) cases for congenital hypothyroidism, 1(3.33%) case for hyperthyroidism, 1(3.33%) case for hyperthyroidism-Graves disease, 8(26.7%) cases for hypothyroidism and 4(13.3%) cases for subclinical hypothyroidism.

Keywords: Thyroid disorders; children; hyperthyroidism; hypothyroidism.

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Conflict of interest statement

None to declare.

Figures

Figure 1
Figure 1
Age distribution among patients
Figure 2
Figure 2
Age distribution among gender of patients
Figure 3
Figure 3
Distribution of TSH values according to each diagnosis
Figure 4
Figure 4
Distribution of FT4 values according to each diagnosis
Figure 5
Figure 5
Distribution of TPOAb values according to each diagnosis
Figure 6
Figure 6
Distribution of TGAb values according to each diagnosis
Figure 7
Figure 7
The matrix of correlations, calculated for each pair of variables and the p-values corresponding to the significance levels of correlations
See this image and copyright information in PMC

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