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. 2020 Oct;26(4):402-410.
doi: 10.4094/chnr.2020.26.4.402. Epub 2020 Oct 31.

Health-related quality of life of children and adolescents after hematopoietic stem cell transplantationa

Yu Min Hwang  1 , Kyung-Sook Bang  2
Affiliations

Health-related quality of life of children and adolescents after hematopoietic stem cell transplantationa

Yu Min Hwang et al. Child Health Nurs Res. 2020 Oct.

Abstract

Purpose: This study aimed to determine the level of health-related quality of life (HRQoL) of children and adolescents who received hematopoietic stem cell transplantation (HSCT) and to examine factors influencing HRQoL.

Methods: This cross-sectional descriptive study involved 85 participants aged 10 to 19 years who received treatment from 3 months to 5 years after HSCT. Symptom experiences, stress and coping, self-esteem, social support, and HRQoL were measured. Descriptive analysis, the independent t-test, one-way analysis of variance, Pearson correlation analysis, and stepwise multiple regression were used for data analysis.

Results: The mean HRQoL score was 72.26 points out of 100. HRQoL showed statistically significant correlations with symptom experiences, stress, self-esteem, social support, satisfaction with peer relationships, and perceived attentiveness of the medical team. The most influential predictors of HRQoL were symptom experiences (β=-.51, p<.001) and satisfaction with peer relationships (β=.32, p<.001).

Conclusion: The experiences of different symptoms by children and adolescents who receive HSCT must be considered. In addition, nursing interventions, such as self-help meetings with peer groups, should be provided to improve their HRQoL.

Keywords: Adolescent; Child; Hematopoietic stem cell transplantation; Quality of life.

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Conflict of interest statement

Conflict of interest No existing or potential conflict of interest relevant to this article was reported.

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