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Review
. 2021 Dec 24:8:774287.
doi: 10.3389/fvets.2021.774287. eCollection 2021.

Endophyte Infected Tall Fescue: Plant Symbiosis to Animal Toxicosis

Taylor D Ferguson  1 , Eric S Vanzant  1 , Kyle R McLeod  1
Affiliations
Review

Endophyte Infected Tall Fescue: Plant Symbiosis to Animal Toxicosis

Taylor D Ferguson et al. Front Vet Sci. .

Abstract

Endophyte-infected fescue is a major cool season forage used for livestock production in the United States and through other areas of the world. A unique aspect of this forage resource is the symbiotic relationship with an endophytic fungus (Epichloë coenophiala) that has detrimental impact on herbivores due to toxic ergot alkaloids. Research over the past 50 years has unveiled details regarding this symbiotic relationship. This review focuses on the origin of tall fescue in the United States and the consequences of its wide-spread utilization as a livestock forage, along with the discovery and toxicodynamics of ergot alkaloids produced by E. coenophiala. The majority of past ergot alkaloid research has focused on observing phenotypic changes that occur in livestock affected by ergot alkaloids, but recent investigation of the metabolome, transcriptome, and proteome have shown that fescue toxicity-related illnesses are much more complex than previous research suggests.

Keywords: bovine; endophyte; ergot alkaloids; ruminant; tall fescue.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Ergot alkaloids produced by endophytic fungi of the genus Epichloë in infected plants.
See this image and copyright information in PMC

References

    1. Buckner RC, Powell JB, Frakes RV. Historical development. In: Buckner RC, Bush LP, editors>. Tall Fescue. Madison, WI: Agron. Monogr. 20. ASA, CSSA, SSSA; (1978). p. 1–8.
    1. Bush L, Buckner RC. Tall fescue toxicity. In: Matches AG, editor. Anti-Quality Components of Forages. Madison, WI: Spec. Pub. 4. Crop Science Society of America; (1973). p. 99–112.
    1. Hoveland CS. Origin and history. In: Fribourg HA, Hannaway DB, West CP, editors. Tall Fescue for the Twenty-first Century. Madison, WI: Agron. Monogr. 20. ASA, CSSA, SSSA; (2009). p. 3–10.
    1. Smith JG. Meadows and Pastures: Formation and Cultivation in the Middle Eastern States (No. 66). Washington, DC: US Dept of Agriculture; (1899).
    1. Vinall HN. Meadow Fescue: Its Culture and Uses (No. 361-370). Washington, DC: US Dept of Agriculture; (1909).