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Editorial
. 2021 Dec;10(6):893-895.
doi: 10.21037/hbsn-21-412.

Systemic treatment of hepatocellular carcinoma: the times they are a-changin'

Affiliations
Editorial

Systemic treatment of hepatocellular carcinoma: the times they are a-changin'

Claudia Campani et al. Hepatobiliary Surg Nutr. 2021 Dec.
No abstract available

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Conflict of interest statement

Conflicts of Interest: Both authors have completed the ICMJE uniform disclosure form (available at https://dx.doi.org/10.21037/hbsn-21-412). The authors have no conflicts of interest to declare.

Comment on

References

    1. Bruix J, Chan SL, Galle PR, et al. Systemic treatment of hepatocellular carcinoma: An EASL position paper. J Hepatol 2021;75:960-74. 10.1016/j.jhep.2021.07.004 - DOI - PubMed
    1. Finn RS, Qin S, Ikeda M, et al. Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma. N Engl J Med 2020;382:1894-905. 10.1056/NEJMoa1915745 - DOI - PubMed
    1. Ren Z, Xu J, Bai Y, et al. Sintilimab plus a bevacizumab biosimilar (IBI305) versus sorafenib in unresectable hepatocellular carcinoma (ORIENT-32): a randomised, open-label, phase 2-3 study. Lancet Oncol 2021;22:977-90. 10.1016/S1470-2045(21)00252-7 - DOI - PubMed
    1. Sia D, Jiao Y, Martinez-Quetglas I, et al. Identification of an Immune-specific Class of Hepatocellular Carcinoma, Based on Molecular Features. Gastroenterology 2017;153:812-26. 10.1053/j.gastro.2017.06.007 - DOI - PMC - PubMed
    1. Fukumura D, Kloepper J, Amoozgar Z, et al. Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges. Nat Rev Clin Oncol 2018;15:325-40. 10.1038/nrclinonc.2018.29 - DOI - PMC - PubMed