Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Nov 10;9(1):95-97.
doi: 10.1002/mdc3.13359. eCollection 2022 Jan.

Disappearance of Clinical and Imaging Manifestations in Wilson's Disease with Ammonium Tetrathiomolybdate and Zinc

Ignacio J Posada  1 , Ana Ramos  2
Affiliations
Case Reports

Disappearance of Clinical and Imaging Manifestations in Wilson's Disease with Ammonium Tetrathiomolybdate and Zinc

Ignacio J Posada et al. Mov Disord Clin Pract. .
No abstract available

Keywords: Wilson's disease; ceruloplasmin; penicillamine; tetrathiomolybdate.

PubMed Disclaimer

Conflict of interest statement

No specific funding was received for this work and the authors declare that there are no conflicts of interest relevant to this work.

Figures

FIG 1
FIG 1
Axial T2‐weighted brain MR images showing pre‐treatment abnormal bilateral and symmetrical hyperintensities in the lateral thalamus (A), central midbrain (B) and substantia nigra (C) (white arrows) with post‐treatment complete resolution of abnormalities (D, E, F). The hypointensities discussed in the text are not visible in these images.
See this image and copyright information in PMC

References

    1. Mulligan C, Bronstein JM. Wilson disease. An overview and approach to management. Neurol Clin 2020;38(2):417–432. 10.1016/j.ncl.2020.01.005. - DOI - PubMed
    1. Humphries WR, Mills CF, Greig A, Roberts L, Inglis D, Halliday GJ. Use of ammonium tetrathiomolybdate in the treatment of copper poisoning in sheep. Vet Rec 1986;119(24):596–598. - PubMed
    1. Aggarwal A, Bhatt M. Advances in treatment of Wilson disease. Tremor Other Hyperkinet Mov 2018;8:525. 10.7916/D841881D. - DOI - PMC - PubMed
    1. Brewer GJ, Hedera P, Kluin KJ, et al. Treatment of Wilson disease with ammonium tetrathiomolybdate. III. Initial therapy in a total of 55 neurologically affected patients and follow‐up with zinc therapy. Arch Neurol 2003;60(3):379–385. 10.1001/archneur.60.3.379. - DOI - PubMed
    1. De Fabregues O, Viñas J, Palasí A, et al. Ammonium tetrathiomolybdate in the decoppering phase treatment of Wilson's disease with neurological symptoms: A case series. Brain Behav 2020;10(5):e01596. 10.1002/brb3.1596. - DOI - PMC - PubMed

Publication types

LinkOut - more resources