Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Jun 8;6(2):133-139.
doi: 10.14744/bej.2021.56338. eCollection 2021.

Posterior Scleritis Simulating Choroidal Melanoma: A Case Report

Simanta Khadka  1 , Raghunandan Byanju  1 , Sangita Pradhan  1
Affiliations
Case Reports

Posterior Scleritis Simulating Choroidal Melanoma: A Case Report

Simanta Khadka et al. Beyoglu Eye J. .

Abstract

Nodular posterior scleritis (NPS) is rare; however, it is critical to differentiate it from similar intraocular pathologies to prevent inappropriate and potentially irreversible treatment. Multimodal imaging is beneficial in the diagnosis of NPS. This report describes the diagnosis and management of a case of NPS with corticosteroid therapy that led to complete resolution.

Keywords: Choroidal melanoma; corticosteroids; nodular posterior scleritis; simulating lesion.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Fundus photography. (a) Right eye within normal limits, (b) left eye with visible mass located inside the boundary of the temporal arcade, (c) wide field photography of the left eye, (d) fundus autofluorescence of the left eye revealing the mass lesion with autofluorescent properties.
Figure 2
Figure 2
B scan ultrasonographic image of the mass lesion. (a) The lesion can be seen temporal to the disc (white arrowheads), (b) largest dimension of the mass lesion.
Figure 3
Figure 3
Optical coherence tomography of the left eye illustrating the dome-shaped solitary nodular lesion and multifocal exudative detachment of the retina.
Figure 4
Figure 4
Fundus fluorescein angiography (FFA) and indocyanine green angiography (ICGA). (a) Early-phase images reveal blocked hypofluorescence of the choroidal mass with multiple leakage sites within and surrounding the mass. (b) Late-phase images show diffuse hypofluorescence with multiple pinpoint leakage sites seen with FFA and pooling of dye with ICGA, suggestive of exudative detachment.
Figure 5
Figure 5
Magnetic resonance imaging of the orbit. (a, b) T1-weighted hyperintensity of the lesion, (c) T2-weighted image revealing hypointense mass lesion, (d) post gadolinium contrast image showing diffuse enhancement of the lesion as well as enhancement of surrounding periocular tissue posterior to the globe.
Figure 6
Figure 6
Fundus photograph and corresponding optical coherence tomography of the left eye after 1 year. The lesion has completely regressed and near-normal restoration of the foveal anatomy was achieved.
See this image and copyright information in PMC

References

    1. Sin PY, Liu DT, Young AL. Nodular posterior scleritis mimicking choroidal tumor in a patient with systemic lupus erythematous:a case report and literature review. Asia Pac J Ophthalmol (Phila) 2016;5:324–9. - PubMed
    1. Biswas J, Mittal S, Ganesh SK, Shetty NS, Gopal L. Posterior scleritis:clinical profile and imaging characteristics. Indian J Ophthalmol. 1998;46:195–202. - PubMed
    1. Benson WE. Posterior scleritis. Surv Ophthalmol. 1988;32:297–316. - PubMed
    1. Lavric A, Gonzalez-Lopez JJ, Majumder PD, Bansal N, Biswas J, Pavesio C, et al. Posterior scleritis:analysis of epidemiology, clinical factors, and risk of recurrence in a cohort of 114 patients. Ocul Immunol Inflamm. 2016;24:6–15. - PubMed
    1. McCluskey PJ, Watson PG, Lightman S, Haybittle J, Restori M, Branley M. Posterior scleritis:clinical features, systemic associations, and outcome in a large series of patients. Ophthalmology. 1999;106:2380–6. - PubMed

Publication types

LinkOut - more resources