Artemisinin resistance in Africa: How urgent is the threat?
- PMID: 35005674
- PMCID: PMC8729812
- DOI: 10.1016/j.medj.2021.11.005
Artemisinin resistance in Africa: How urgent is the threat?
Abstract
Malaria is unrelenting in its impact on sub-Saharan Africa, with an estimated 215 million cases and 384,000 deaths in 2019, mostly in young children. Although devastating, this situation represents a halving in incidence and mortality compared to the early 2000s, associated with continent-wide implementation of effective artemisinin (ART)-based combination therapies (ACTs) and enhanced mosquito vector control measures. Now, however, clinically confirmed ART resistance has emerged in Rwanda and northern Uganda.
Conflict of interest statement
DECLARATION OF INTERESTS The authors declare no competing interests.
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