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Comment
. 2022 Jan;18(1):67-68.
doi: 10.1007/s13181-021-00872-1. Epub 2022 Jan 10.

The Cents of the Dosage Cap in Patients Greater than 100 Kilograms Receiving N-Acetylcysteine for Acetaminophen Toxicity

Regan A Baum  1 , Mark K Su  2 , Kyle A Weant  3
Affiliations
Comment

The Cents of the Dosage Cap in Patients Greater than 100 Kilograms Receiving N-Acetylcysteine for Acetaminophen Toxicity

Regan A Baum et al. J Med Toxicol. 2022 Jan.
No abstract available

Keywords: Acetaminophen; Capped dosing; Hepatotoxicity; NAC; Obesity.

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Conflict of interest statement

None.

Figures

Fig. 1
Fig. 1
N-acetylcysteine dose and estimated vial costs of the proposed optimized dosing regimen compared with the combined preparation of the first two infusion bags.
See this image and copyright information in PMC

Comment on

References

    1. Baum RA, et al. Evaluation of dosing strategies of N-acetylcysteine for acetaminophen toxicity in patients greater than 100 kilograms: should the dosage cap be used? J Med Toxicol. 2021;17(3):241–249. doi: 10.1007/s13181-021-00822-x. - DOI - PMC - PubMed
    1. Johnson MT, et al. Evaluation of a simplified N-acetylcysteine dosing regimen for the treatment of acetaminophen toxicity. Ann Pharmacother. 2011;45(6):713–720. doi: 10.1345/aph.1P613. - DOI - PubMed
    1. ACETADOTE (acetylcysteine) injection (package insert). 2019; Available from: https://www.acetadote.com/New_Acetadote_Labeling_25OCT2019.pdf. Accessed 12/9/21

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