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. 2021 Dec 24;11(1):98.
doi: 10.3390/jcm11010098.

Tidal Volume in Pediatric Ventilation: Do You Get What You See?

Affiliations

Tidal Volume in Pediatric Ventilation: Do You Get What You See?

Erik Koomen et al. J Clin Med. .

Abstract

Mechanical ventilators are increasingly evolving into computer-driven devices. These technical advancements have impact on clinical decisions in pediatric intensive care units (PICUs). A good understanding of the design of mechanical ventilators can improve clinical care. Tidal volume (TV) is one of the corner stones of ventilation: multiple technical factors influence the TV and, thus, influence clinical decision making. Ventilator manufacturers make various design choices regarding the phase, site and conditions of TV measurement as well as algorithmic processing choices. Such choice may impact the measurement and subsequent display of TV. A software change of the TV measuring algorithm of the SERVO-i® (Getinge, Solna, Sweden) at the PICU of the University Medical Centre Utrecht was studied in a prospective cohort. It showed, as example, a clinically significant impact of 8% difference in reported TV. Design choices in both the hardware and software of mechanical ventilators can have a clinically relevant impact on the measurement of tidal volume. In our search for the optimal TV for lung-protective ventilation, such choices should be taken into account.

Keywords: clinical perception of technique; pediatric ventilation; software; technical challenges.

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Conflict of interest statement

E.K. has received consulting/speaker honorarium from Philips, GE Healthcare, Getinge, B Braun in the past. Getinge had no involvement in this study, only provided general open information about software version 7.0 of the SERVO-i®. The other authors declare that they have no competing interests.

Figures

Figure 1
Figure 1
Schematic example of a ventilator displaying tidal volume (VT) under ATPD (A) versus BTPS (B) conditions in a ventilated infant. In (A), inspiratory V was sensed and displayed as 40 mL, however, after heating and humidifying of the gas, the actual delivered VT was 45 mL. In (B), inspiratory VT was sensed as 36 mL, but after a (software) correction displayed and delivered as 40 mL.

References

    1. Castle R.A., Dunne C.J., Mok Q., Wade A.M., Stocks J. Accuracy of Displayed Values of Tidal Volume in the Pediatric Intensive Care Unit. Crit. Care Med. 2002;30:2566–2574. doi: 10.1097/00003246-200211000-00027. - DOI - PubMed
    1. Guyton . Textbook of Medical Physiology. 11th ed. Sigma-Aldrich; St. Louis, MI, USA: 2005. [(accessed on 26 October 2021)]. Available online: http://www.sigmaaldrich.com/
    1. Michael Badgwell J., Swan J., Foster A.C. Volume-Controlled Ventilation Is Made Possible in Infants by Using Compliant Breathing Circuits with Large Compression Volume. Anesth. Analg. 1996;82:719–723. doi: 10.1097/00000539-199604000-00007. - DOI - PubMed
    1. Wheeler K.I., Klingenberg C., Morley C.J., Davis P.G. Volume-Targeted versus Pressure-Limited Ventilation for Preterm Infants: A Systematic Review and Meta-Analysis. Neonatology. 2011;100:219–227. doi: 10.1159/000326080. - DOI - PubMed
    1. Klingenberg C., Wheeler K.I., Davis P.G., Morley C.J. A Practical Guide to Neonatal Volume Guarantee Ventilation. J. Perinatol. 2011;31:575–585. doi: 10.1038/jp.2011.98. - DOI - PubMed

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