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. 2021 Dec 29;11(1):167.
doi: 10.3390/jcm11010167.

Physical Activity and Diet Quality: Effects on Cardiovascular Morbidity in Women with Turner Syndrome-Results from an Online Patient Survey

Leonie Arnold  1 , Martina Bacova  1 , Robert Dalla-Pozza  1 , Nikolaus Alexander Haas  1 , Felix Sebastian Oberhoffer  1
Affiliations

Physical Activity and Diet Quality: Effects on Cardiovascular Morbidity in Women with Turner Syndrome-Results from an Online Patient Survey

Leonie Arnold et al. J Clin Med. .

Abstract

Turner syndrome (TS) is a rare chromosomal disease with increased cardiovascular morbidity and mortality. The aim of this study was to investigate the influence of physical activity and diet quality on cardiovascular morbidity in German TS women. An anonymous online questionnaire was established. The questionnaire was based on the 2020 WHO recommendations on physical activity and sedentary behaviour and included the 14-Item Mediterranean Diet Assessment Tool. In addition, TS patients were asked about existing cardiovascular conditions. In total, 83 TS women were included in the final analysis. The achievement of <600 Metabolic Equivalent-minutes per week for recreational activities was significantly associated with the presence of arterial hypertension (p = 0.006). High adherence to the Mediterranean diet was achieved by only 20.5% of TS subjects and tended to be inversely associated with the presence of lipid metabolism disorders (p = 0.063). Only 37.3% of TS participants received nutritional counselling. Given the increased cardiovascular risk, specific counselling for lifestyle optimisation may play an important role in the management of TS. Further studies are required to evaluate the effects of regular aerobic physical training and different nutritional programs on cardiovascular morbidity in TS.

Keywords: Turner syndrome; cardiovascular morbidity; diet quality; physical activity.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
MET-minutes per week for recreational activities and cardiovascular morbidity in Turner syndrome patients. Chi-squared tests or Fisher’s exact test for counts smaller than five were applied to test for significance. ** p ≤ 0.01.
Figure 2
Figure 2
MET-minutes per week for recreational activities relative to weight classification of Turner syndrome patients. Chi-squared tests or Fisher’s exact test for counts smaller than five were applied to test for significance.
Figure 3
Figure 3
Low (score ≤ 7) and high (score > 7) adherence to the Mediterranean diet relative to cardiovascular morbidity in Turner syndrome patients. Chi-squared tests or Fisher’s exact test for counts smaller than five were applied to test for significance.
See this image and copyright information in PMC

References

    1. Sybert V.P., McCauley E. Turner’s syndrome. N. Engl. J. Med. 2004;351:1227–1238. doi: 10.1056/NEJMra030360. - DOI - PubMed
    1. Gravholt C.H., Andersen N.H., Conway G.S., Dekkers O.M., Geffner M.E., Klein K.O., Lin A.E., Mauras N., Quigley C.A., Rubin K., et al. Clinical practice guidelines for the care of girls and women with Turner syndrome: Proceedings from the 2016 Cincinnati International Turner Syndrome Meeting. Eur. J. Endocrinol. 2017;177:G1–G70. doi: 10.1530/EJE-17-0430. - DOI - PubMed
    1. Mavinkurve M., O’Gorman C.S. Cardiometabolic and vascular risks in young and adolescent girls with Turner syndrome. BBA Clin. 2015;3:304–309. doi: 10.1016/j.bbacli.2015.04.005. - DOI - PMC - PubMed
    1. Mitchell G.F., Hwang S.-J., Vasan R.S., Larson M.G., Pencina M.J., Hamburg N.M., Vita J.A., Levy D., Benjamin E.J. Arterial stiffness and cardiovascular events: The Framingham Heart Study. Circulation. 2010;121:505–511. doi: 10.1161/CIRCULATIONAHA.109.886655. - DOI - PMC - PubMed
    1. Oberhoffer F.S., Abdul-Khaliq H., Jung A.-M., Rohrer T.R., Abd El Rahman M. Two-dimensional speckle tracking of the abdominal aorta: A novel approach to evaluate arterial stiffness in patients with Turner syndrome. Cardiovasc. Diagn. Ther. 2019;9:S228–S237. doi: 10.21037/cdt.2019.03.01. - DOI - PMC - PubMed

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