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. 2022 Jan 10:376:e055924.
doi: 10.1136/bmj-2021-055924.

Management and outcomes of extreme preterm birth

Andrei S Morgan  1   2   3 , Marina Mendonça  4   5 , Nicole Thiele  6 , Anna L David  2   7
Affiliations

Management and outcomes of extreme preterm birth

Andrei S Morgan et al. BMJ. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Competing interests: We have read and understood The BMJ policy on declaration of interests and declare that we have no competing interests.

Figures

Fig 1
Fig 1
Survival for fetuses alive at maternal admission to hospital born at 22-23, 24, 25, and 26 weeks’ gestation in national cohorts from Sweden (EXPRESS, 2004-07), England (EPICure-2, 2006), and France (EPIPAGE-2, 2011). Adapted from Morgan et al, 2021
Fig 2
Fig 2
Approximate effect sizes for the impact of very preterm birth (<32 weeks’ gestation) on long term outcomes (compared with birth at term; zero vertical line). Effect sizes are defined as small (odds ratio (OR) 1.48 or inverted 0.67; Cohen’s d between means 0.2), moderate (OR 3.45 or 0.29, Cohen’s d 0.5), or large (OR 9.00 or 0.11, Cohen’s d 0.8). Outcomes assessed in childhood and adolescence are shown in turquoise and outcomes assessed in adulthood in orange. ADHD=attention deficit/hyperactivity disorder; ASD=autism spectrum disorder; DCD=developmental coordination disorder; HRQoL=health related quality of life; IQ=intelligence quotient; SEN=special educational needs. Figure and caption adapted from Wolke et al, 2019
See this image and copyright information in PMC

References

    1. World Health Organization. Preterm birth factsheet. 2018. https://www.who.int/news-room/fact-sheets/detail/preterm-birth.
    1. Morgan AS, Waheed S, Gajree S, Marlow N, David AL. Maternal and infant morbidity following birth before 27 weeks of gestation: a single centre study. Sci Rep 2021;11:288. 10.1038/s41598-020-79445-1 - DOI - PMC - PubMed
    1. Torchin H, Morgan AS, Ancel P-Y. International comparisons of neurodevelopmental outcomes in infants born very preterm. Semin Fetal Neonatal Med 2020;25:101109. 10.1016/j.siny.2020.101109 - DOI - PubMed
    1. Morgan AS, Zeitlin J, Kallen K, et al. Birth outcomes between 22-26 weeks’ gestation in national population-based cohorts from Sweden, England and France. Acta Paediatrica 2021;00:1-17 10.1111/apa.16084 - DOI - PMC - PubMed
    1. Chawanpaiboon S, Vogel JP, Moller A-B, et al. . Global, regional, and national estimates of levels of preterm birth in 2014: a systematic review and modelling analysis. Lancet Glob Health 2019;7:e37-46. 10.1016/S2214-109X(18)30451-0 - DOI - PMC - PubMed

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