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Comment
. 2022 Jan;28(1):53-58.
doi: 10.1038/s41591-021-01639-5. Epub 2022 Jan 10.

Reply to: Concerns about estimating relative risk of death associated with convalescent plasma for COVID-19

Philippe Bégin #  1   2 , Jeannie Callum #  3   4   5   6 , Richard Cook  7 , Erin Jamula  8 , Yang Liu  8 , Andrés Finzi  9   10 ; CONCOR-1 Study Group; Donald M Arnold #  11   12
Collaborators, Affiliations
Comment

Reply to: Concerns about estimating relative risk of death associated with convalescent plasma for COVID-19

Philippe Bégin et al. Nat Med. 2022 Jan.
No abstract available

PubMed Disclaimer

Comment on

  • Convalescent Plasma Antibody Levels and the Risk of Death from Covid-19.
    Joyner MJ, Carter RE, Senefeld JW, Klassen SA, Mills JR, Johnson PW, Theel ES, Wiggins CC, Bruno KA, Klompas AM, Lesser ER, Kunze KL, Sexton MA, Diaz Soto JC, Baker SE, Shepherd JRA, van Helmond N, Verdun NC, Marks P, van Buskirk CM, Winters JL, Stubbs JR, Rea RF, Hodge DO, Herasevich V, Whelan ER, Clayburn AJ, Larson KF, Ripoll JG, Andersen KJ, Buras MR, Vogt MNP, Dennis JJ, Regimbal RJ, Bauer PR, Blair JE, Paneth NS, Fairweather D, Wright RS, Casadevall A. Joyner MJ, et al. N Engl J Med. 2021 Mar 18;384(11):1015-1027. doi: 10.1056/NEJMoa2031893. Epub 2021 Jan 13. N Engl J Med. 2021. PMID: 33523609 Free PMC article.
  • Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial.
    Bégin P, Callum J, Jamula E, Cook R, Heddle NM, Tinmouth A, Zeller MP, Beaudoin-Bussières G, Amorim L, Bazin R, Loftsgard KC, Carl R, Chassé M, Cushing MM, Daneman N, Devine DV, Dumaresq J, Fergusson DA, Gabe C, Glesby MJ, Li N, Liu Y, McGeer A, Robitaille N, Sachais BS, Scales DC, Schwartz L, Shehata N, Turgeon AF, Wood H, Zarychanski R, Finzi A; CONCOR-1 Study Group; Arnold DM. Bégin P, et al. Nat Med. 2021 Nov;27(11):2012-2024. doi: 10.1038/s41591-021-01488-2. Epub 2021 Sep 9. Nat Med. 2021. PMID: 34504336 Free PMC article. Clinical Trial.
  • Concerns about estimating relative risk of death associated with convalescent plasma for COVID-19.
    Joyner MJ, Paneth NS, Senefeld JW, Fairweather D, Bruno KA, Wright RS, Carter RE, Casadevall A. Joyner MJ, et al. Nat Med. 2022 Jan;28(1):51-52. doi: 10.1038/s41591-021-01638-6. Epub 2022 Jan 10. Nat Med. 2022. PMID: 35013614 No abstract available.

References

    1. Begin, P. et al. Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial. Nat. Med. 27, 2012–2024 (2021).
    1. Yusuf, S., Wittes, J., Probstfield, J. & Tyroler, H. A. Analysis and interpretation of treatment effects in subgroups of patients in randomized clinical trials. J. Am. Med. Assoc. 266, 93–98 (1991). - DOI
    1. Korley, F.K. et al. Early convalescent plasma for high-risk outpatients with Covid-19. N. Engl. J. Med. https://doi.org/10.1056/NEJMoa2103784 (2021).
    1. The RECOVERY Collaborative Group, et al. Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. Lancet 397, 2049–2059 https://doi.org/10.1016/S0140-6736(21)00897-7 (2021).
    1. Writing Committee for the REMAP-CAP Investigators, et al. Effect of convalescent plasma on organ support-free days in critically ill patients with COVID-19: a randomized clinical trial. J. Am. Med. Assoc. https://doi.org/10.1001/jama.2021.18178 (2021).

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