Correction to: Transplantation of mesenchymal stem cells genetically engineered to overexpress interleukin-10 promotes alternative inflammatory response in rat model of traumatic brain injury

S T Peruzzaro^{1

2}, M M M Andrews^#^{1

2}, A Al-Gharaibeh^#^{1

2}, O Pupiec^{1

2}, M Resk^{1

2}, D Story^{1

2

3}, P Maiti^{1

2

3

4

5

6}, J Rossignol^{7

8

9}, G L Dunbar^{10

11

12

13

14}

Affiliations

¹ Field Neurosciences Institute Laboratory for Restorative Neurology, Central Michigan University, Mt. Pleasant, MI, 48859, USA.
² Program in Neuroscience, Central Michigan University, Mt. Pleasant, MI, 48859, USA.
³ Department of Psychology, Central Michigan University, Mt. Pleasant, MI, 48859, USA.
⁴ Field Neurosciences Institute, St. Mary's of Michigan, Saginaw, MI, 48604, USA.
⁵ Department of Biology, Saginaw Valley State University, Saginaw, MI, 48610, USA.
⁶ Brain Research Laboratory, Saginaw Valley State University, Saginaw, MI, 48610, USA.
⁷ Field Neurosciences Institute Laboratory for Restorative Neurology, Central Michigan University, Mt. Pleasant, MI, 48859, USA. rossi1j@cmich.edu.
⁸ Program in Neuroscience, Central Michigan University, Mt. Pleasant, MI, 48859, USA. rossi1j@cmich.edu.
⁹ College of Medicine, Central Michigan University, Mt. Pleasant, MI, 48859, USA. rossi1j@cmich.edu.
¹⁰ Field Neurosciences Institute Laboratory for Restorative Neurology, Central Michigan University, Mt. Pleasant, MI, 48859, USA. dunba1g@cmich.edu.
¹¹ Program in Neuroscience, Central Michigan University, Mt. Pleasant, MI, 48859, USA. dunba1g@cmich.edu.
¹² Department of Psychology, Central Michigan University, Mt. Pleasant, MI, 48859, USA. dunba1g@cmich.edu.
¹³ Field Neurosciences Institute, St. Mary's of Michigan, Saginaw, MI, 48604, USA. dunba1g@cmich.edu.
¹⁴ Brain Research Laboratory, Saginaw Valley State University, Saginaw, MI, 48610, USA. dunba1g@cmich.edu.

^# Contributed equally.

PMID: 35016685
PMCID: PMC8753833
DOI: 10.1186/s12974-021-02362-1

Published Erratum

Correction to: Transplantation of mesenchymal stem cells genetically engineered to overexpress interleukin-10 promotes alternative inflammatory response in rat model of traumatic brain injury

S T Peruzzaro et al. J Neuroinflammation. 2022.

. 2022 Jan 11;19(1):15.

doi: 10.1186/s12974-021-02362-1.

Authors

Affiliations

¹ Field Neurosciences Institute Laboratory for Restorative Neurology, Central Michigan University, Mt. Pleasant, MI, 48859, USA.
² Program in Neuroscience, Central Michigan University, Mt. Pleasant, MI, 48859, USA.
³ Department of Psychology, Central Michigan University, Mt. Pleasant, MI, 48859, USA.
⁴ Field Neurosciences Institute, St. Mary's of Michigan, Saginaw, MI, 48604, USA.
⁵ Department of Biology, Saginaw Valley State University, Saginaw, MI, 48610, USA.
⁶ Brain Research Laboratory, Saginaw Valley State University, Saginaw, MI, 48610, USA.
⁷ Field Neurosciences Institute Laboratory for Restorative Neurology, Central Michigan University, Mt. Pleasant, MI, 48859, USA. rossi1j@cmich.edu.
⁸ Program in Neuroscience, Central Michigan University, Mt. Pleasant, MI, 48859, USA. rossi1j@cmich.edu.
⁹ College of Medicine, Central Michigan University, Mt. Pleasant, MI, 48859, USA. rossi1j@cmich.edu.
¹⁰ Field Neurosciences Institute Laboratory for Restorative Neurology, Central Michigan University, Mt. Pleasant, MI, 48859, USA. dunba1g@cmich.edu.
¹¹ Program in Neuroscience, Central Michigan University, Mt. Pleasant, MI, 48859, USA. dunba1g@cmich.edu.
¹² Department of Psychology, Central Michigan University, Mt. Pleasant, MI, 48859, USA. dunba1g@cmich.edu.
¹³ Field Neurosciences Institute, St. Mary's of Michigan, Saginaw, MI, 48604, USA. dunba1g@cmich.edu.
¹⁴ Brain Research Laboratory, Saginaw Valley State University, Saginaw, MI, 48610, USA. dunba1g@cmich.edu.

^# Contributed equally.

PMID: 35016685
PMCID: PMC8753833
DOI: 10.1186/s12974-021-02362-1

No abstract available

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Figures

**Fig. 5**
Astrocytes labelled with GFAP antibody in the frontal cortex and hippocampus. A A significant reduction in GFAP-positive cells was seen in TBI + MSCs (***p < 0.001) and TBI + MSCs + IL-10 (***p < 0.001) groups in the frontal cortex in comparison to TBI + vehicle group. B In the CA1 region of the hippocampus, a significant reduction of GFAP positive cells were found in the TBI + MSCs + IL-10 (***p < 0.001) and sham + vehicle group (*p < 0.05) in comparison to TBI + vehicle group. C In the CA3 region of the hippocampus, TBI + vehicle group had a significant increase in GFAP-positive cells when compared to all other groups (*p < 0.05, **p < 0.01; scale bar = 50 µm). Error bars represent ± SEM

**Fig. 6**
Macrophages/microglia labelled with Iba1 antibody in the frontal cortex and hippocampus. A In the frontal cortex an injury effect was seen with an increased number of Iba1 positive cells in all TBI groups (*p < 0.05, ***p < 0.001). B No significant differences were seen among the groups in the CA1 region of the hippocampus. C No significant differences were seen among the groups in the CA3 region of the hippocampus (scale bar = 50 µm). Error bars represent ± SEM

See this image and copyright information in PMC

Erratum for

Transplantation of mesenchymal stem cells genetically engineered to overexpress interleukin-10 promotes alternative inflammatory response in rat model of traumatic brain injury.
Peruzzaro ST, Andrews MMM, Al-Gharaibeh A, Pupiec O, Resk M, Story D, Maiti P, Rossignol J, Dunbar GL. Peruzzaro ST, et al. J Neuroinflammation. 2019 Jan 5;16(1):2. doi: 10.1186/s12974-018-1383-2. J Neuroinflammation. 2019. PMID: 30611291 Free PMC article.

References

1. Peruzzaro ST, Andrews MM, Al-Gharaibeh A, Pupiec O, Resk M, Story D, Maiti P, Rossignol J, Dunbar GL. Transplantation of mesenchymal stem cells genetically engineered to overexpress interleukin-10 promotes alternative inflammatory response in rat model of traumatic brain injury. J Neuroinflamm. 2019;16:2. doi: 10.1186/s12974-018-1383-2. - DOI - PMC - PubMed

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Correction to: Transplantation of mesenchymal stem cells genetically engineered to overexpress interleukin-10 promotes alternative inflammatory response in rat model of traumatic brain injury

Affiliations

Correction to: Transplantation of mesenchymal stem cells genetically engineered to overexpress interleukin-10 promotes alternative inflammatory response in rat model of traumatic brain injury

Authors

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