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Case Reports
. 2021 Nov;13(Suppl 2):S1744-S1746.
doi: 10.4103/jpbs.jpbs_183_21. Epub 2021 Nov 10.

Intraoperative Management of Recurrent Leukoplakia at Red Zone

Affiliations
Case Reports

Intraoperative Management of Recurrent Leukoplakia at Red Zone

S Elengkumaran et al. J Pharm Bioallied Sci. 2021 Nov.

Abstract

Oral leukoplakia (OL) is a potentially malignant oral disorder (PMOD) that sometimes trans-form into oral squamous cell carcinoma (OSCC). OL is one of the most frequent PMODs seen in the oral cavity. The global prevalence of OL is approximately 2.6%, with its worst prognosis of undergoing a malignant transformation. Leukoplakia is clinically divided into red zones (tongue and floor of mouth) and nonred zones (buccal mucosa, palate, and soft palate) areas. The red zone areas have more potency of transforming into malignancy. Hence, patients with red zone areas need to be followed up more frequently and treated appropriately. This case report signifies the importance of treating one such case of leukoplakia at red zone area.

Keywords: Frozen sections; oral squamous cell carcinoma; potentially malignant disorder; premalignant.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Patient photograph depicting the white lesion over the right lateral border of the tongue
Figure 2
Figure 2
Excisional biopsy surgical site
Figure 3
Figure 3
Partial glossectomy with surgical margin clearance
Figure 4
Figure 4
Selective neck lymph node dissection from Group I to IV
Figure 5
Figure 5
Satisfactory wound healing during postsurgical follow-up after 2 weeks

References

    1. Sivapathasundharam B. Shafers's Textbook of Oral Pathology. 8th ed. 4. Elsevier India: Elsevier Inc; 2016. pp. 136–50.
    1. Messadi DV. Diagnostic aids for detection of oral precancerous conditions. Int J Oral Sci. 2013;5:59–65. - PMC - PubMed
    1. Favia G, Capodiferro S, Limongelli L, Tempesta A, Maiorano E. Malignant transformation of oral proliferative verrucous leukoplakia: A series of 48 patients with suggestions for management. Int J Oral Maxillofac Surg. 2021;50:14–20. - PubMed
    1. Chaturvedi P, Singh B, Nair S, Nair D, Kane SV, D'cruz A, et al. Utility of frozen section in assessment of margins and neck node metastases in patients undergoing surgery for carcinoma of the tongue. J Cancer Res Ther. 2012;8(Suppl 1):S100–5. - PubMed
    1. Kuribayashi Y, Tsushima F, Sato M, Morita K, Omura K. Recurrence patterns of oral leukoplakia after curative surgical resection: Important factors that predict the risk of recurrence and malignancy. J Oral Pathol Med. 2012;41:682–8. - PubMed

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