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Review
. 2021 Apr-Jun;16(2):91-96.
doi: 10.4103/jpn.JPN_137_20. Epub 2021 Jul 2.

Electrical Status Epilepticus During Slow-wave Sleep (ESES): Current Perspectives

Pinar Arican  1 , Pinar Gencpinar  2 , Nihal Olgac Dundar  2 , Hasan Tekgul  3
Affiliations
Review

Electrical Status Epilepticus During Slow-wave Sleep (ESES): Current Perspectives

Pinar Arican et al. J Pediatr Neurosci. 2021 Apr-Jun.

Abstract

Electrical status epilepticus during slow-wave sleep (ESES) is an epilepsy syndrome with sleep-induced epileptic discharges and acquired impairment of cognition or behavior. Since the disease's original description in 1971, no clear consensus has emerged on diagnostic criteria or optimal treatment. The treatment of ESES can be challenging, often including numerous antiepileptic drugs, immunomodulatory agents, and even surgical interventions. There is little evidence to guide treatment because only retrospective studies and case reports on the efficacy of treatment of ESES are present in literature. In this paper, we aim to analyze the etiopathogenesis of ESES in the new genetic era and to evaluate the treatment modalities in accordance with the genetic data and electroclinic spectrum of ESES.

Keywords: ESES; Epilepsy; etiology; treatment.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Reported etiologies of ESES
Figure 2
Figure 2
Reported type of seizures in patients with ESES
See this image and copyright information in PMC

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