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Review
. 2022 Apr;35(2):131-156.
doi: 10.37201/req/083.2021. Epub 2022 Jan 12.

Past and future of HIV infection. A document based on expert opinion

E Bouza  1 , J R Arribas, B Alejos, J I Bernardino, M Coiras, P Coll, J Del Romero, M J Fuster, M Górgolas, A Gutiérrez, D Gracia, V Hernando, J Martínez-Picado, J M Martínez Sesmero, E Martínez, S Moreno, B Mothe, M L Navarro, D Podzamczer, F Pulido, J T Ramos, E Ruiz-Mateos, I Suárez García, E Palomo
Affiliations
Review

Past and future of HIV infection. A document based on expert opinion

E Bouza et al. Rev Esp Quimioter. 2022 Apr.

Abstract
in English, Spanish

HIV infection is now almost 40 years old. In this time, along with the catastrophe and tragedy that it has entailed, it has also represented the capacity of modern society to take on a challenge of this magnitude and to transform an almost uniformly lethal disease into a chronic illness, compatible with a practically normal personal and relationship life. This anniversary seemed an ideal moment to pause and reflect on the future of HIV infection, the challenges that remain to be addressed and the prospects for the immediate future. This reflection has to go beyond merely technical approaches, by specialized professionals, to also address social and ethical aspects. For this reason, the Health Sciences Foundation convened a group of experts in different aspects of this disease to discuss a series of questions that seemed pertinent to all those present. Each question was presented by one of the participants and discussed by the group. The document we offer is the result of this reflection.

La infección por VIH cumple ahora casi 40 años de exist-encia. En este tiempo, junto a la catástrofe y la tragedia que ha supuesto, ha representado también la capacidad de la sociedad moderna de asumir un reto de esta magnitud y de transformar, gracias al tratamiento antirretroviral, una enfermedad mayor-itariamente letal en una enfermedad crónica, compatible con una vida personal y de relación prácticamente normales. Este aniversario parecía un momento idóneo para pararse a reflex-ionar sobre el futuro de la infección VIH, los retos que todavía quedan por abordar y las perspectivas para el inmediato futuro. Esa reflexión tiene que ir más allá de planteamientos meramente técnicos, de profesionales especializados, para abordar aspectos sociales y éticos. Por este motivo, la Fundación de Ciencias de la Salud convocó a un grupo de expertos en distintos aspectos de esta infección para discutir una serie de preguntas que pare-cieron pertinentes a todos los convocados. Cada pregunta era expuesta por uno de los participantes y discutida por el grupo. El documento que ofrecemos es el resultado de esa reflexión.

Keywords: AIDS; HIV infection; chronic disease; epidemiology; eradication; history; immunotherapy; prevention; two-drug treatment; vaccine.

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Conflict of interest statement

The authors declare no conflicts of interest

Figures

Figure 1
Figure 1
Sandoval Centre 2018. HIV seroprevalence at first visit, by exposure category. N= 4,529 people (1st consultation). MSM: Men who have sex with men; TSX: Transgender people; MSW: Male sex workers, TSW: Transgender sex workers; HTX: Heterosexual; FSW: Female sex workers
See this image and copyright information in PMC

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