Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2022 Dec 1;276(6):e1118-e1119.
doi: 10.1097/SLA.0000000000005367. Epub 2022 Jan 11.

Comment on: "A Randomized Clinical Trial Evaluating the Efficacy and Quality of Life of Antibiotic-only Treatment of Acute Uncomplicated Appendicitis: Results of the COMMA Trial"

Chenhao Hu  1   2   3 , Zhe Zhang  1   2   3 , Feiyu Shi  1   2   3 , Lei Zhang  1   2   3 , Junjun She  1   2   3
Affiliations
Comment

Comment on: "A Randomized Clinical Trial Evaluating the Efficacy and Quality of Life of Antibiotic-only Treatment of Acute Uncomplicated Appendicitis: Results of the COMMA Trial"

Chenhao Hu et al. Ann Surg. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors report no conflicts of interest.

Comment in

  • Response to Letter to Editor.
    O'Leary DP, Hill A. O'Leary DP, et al. Ann Surg. 2022 Dec 1;276(6):e1119-e1120. doi: 10.1097/SLA.0000000000005368. Epub 2022 Jan 11. Ann Surg. 2022. PMID: 35020679 No abstract available.

Comment on

References

    1. O’Leary DP, Walsh SM, Bolger J, et al. A randomized clinical trial evaluating the efficacy and quality of life of antibiotic-only treatment of acute uncomplicated appendicitis: results of the COMMA trial. Ann Surg. 2021;274:240–247.
    1. Hansson J, Korner U, Khorram-Manesh A, et al. Randomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients. Br J Surg. 2009;96:473–481.
    1. Girard-Madoux MJH, Gomez de Aguero M, Ganal-Vonarburg SC, et al. The immunological functions of the Appendix: an example of redundancy? Semin Immunol. 2018;36:31–44.
    1. Sanchez-Alcoholado L, Fernandez-Garcia JC, Gutierrez-Repiso C, et al. Incidental prophylactic appendectomy is associated with a profound microbial dysbiosis in the long-term. Microorganisms. 2020;8:609.
    1. Park HC, Kim MJ, Lee BH. Randomized clinical trial of antibiotic therapy for uncomplicated appendicitis. Br J Surg. 2017;104:1785–1790.

Substances