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. 2022 Mar 28;38(7):2052-2053.
doi: 10.1093/bioinformatics/btac022.

ProSynAR: a reference aware read merger

Benjamin Crysup  1 , Bruce Budowle  1 , August E Woerner  1
Affiliations

ProSynAR: a reference aware read merger

Benjamin Crysup et al. Bioinformatics. .

Abstract

Motivation: Read-merging algorithms that look solely at the reads can misalign and mis-merge the reads (especially near repetitive sequences).

Results: The C++ program ProSynAR has been written to take the reads' position in the reference into account when performing (and deciding whether to perform) a merge.

Availability: *Nix users can retrieve the source from GitHub (https://github.com/Benjamin-Crysup/prosynar). Windows binary available at https://github.com/Benjamin-Crysup/prosynar/releases/download/1.0/prosynar.zip.

Supplementary information: Supplementary data are available at Bioinformatics online.

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