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Editorial
. 2022 Apr 1;225(7):1301-1302.
doi: 10.1093/infdis/jiab571.

Human Cytomegalovirus and Risk of Incident Cardiovascular Disease in UK Biobank

Affiliations
Editorial

Human Cytomegalovirus and Risk of Incident Cardiovascular Disease in UK Biobank

Tom A Yates et al. J Infect Dis. .
No abstract available

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Figures

Figure 1.
Figure 1.
(A) Schematic demonstrating an in-sample negative correlation (filled circles and dashed line) that does not exist in the underlying population (all circles) may be generated by selectively including individuals with lower levels of both exposure and outcome. (B) Simulated data showing how in-sample associations (dashed line) may not reflect population level associations (line) if selected individuals (crosses) are a specific subset of the population (triangles).

Comment in

  • Reply to letter Yates et al.
    Hamilton EM, Allen NE, Mentzer AJ, Littlejohns TJ. Hamilton EM, et al. J Infect Dis. 2022 Apr 1;225(7):1303-1304. doi: 10.1093/infdis/jiab572. J Infect Dis. 2022. PMID: 35024816 Free PMC article. No abstract available.

References

    1. Hamilton EM, Allen NE, Mentzer AJ, Littlejohns TJ.. Human cytomegalovirus and risk of incident cardiovascular disease in UK Biobank. J Infect Dis 2022; 225:1179–88. - PMC - PubMed
    1. Fry A, Littlejohns TJ, Sudlow C, et al. . Comparison of sociodemographic and health-related characteristics of UK Biobank participants with those of the general population. Am J Epidemiol 2017; 186:1026–34. - PMC - PubMed
    1. Batty GD, Gale CR, Kivimäki M, Deary IJ, Bell S.. Comparison of risk factor associations in UK Biobank against representative, general population based studies with conventional response rates: prospective cohort study and individual participant meta-analysis. BMJ 2020; 368:1–8. - PMC - PubMed
    1. Cannon MJ, Schmid DS, Hyde TB.. Review of cytomegalovirus seroprevalence and demographic characteristics associated with infection. Rev Med Virol 2010; 20:202–13. - PubMed
    1. Winter JR, Taylor GS, Thomas OG, Jackson C, Lewis JEA, Stagg HR.. Factors associated with cytomegalovirus serostatus in young people in England: a cross-sectional study. BMC Infect Dis 2020; 20:875. - PMC - PubMed

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