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Comment
. 2022 Mar;198(3):319-321.
doi: 10.1007/s00066-021-01899-7. Epub 2022 Jan 13.

[Prophylactic cranial irradiation with or without hippocampal avoidance for small-cell lung cancer (PREMER)- a randomized phase III trial]

[Article in German]
Affiliations
Comment

[Prophylactic cranial irradiation with or without hippocampal avoidance for small-cell lung cancer (PREMER)- a randomized phase III trial]

[Article in German]
Fabian Schunn et al. Strahlenther Onkol. 2022 Mar.
No abstract available

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References

    1. Rodríguez de Dios N, Couñago F, Murcia-Mejía M, Rico-Oses M, Calvo-Crespo P, Samper P, Vallejo C, Luna J, Trueba I, Sotoca A, Cigarral C, Farré N, Manero RM, Durán X, Gispert JD, Sánchez-Benavides G, Rognoni T, Torrente M, Capellades J, Jiménez M, Cabada T, Blanco M, Alonso A, Martínez-San Millán J, Escribano J, González B, López-Guerra JL. Randomized phase III trial of prophylactic cranial irradiation with or without hippocampal avoidance for small-cell lung cancer (PREMER): a GICOR-GOECP-SEOR study. J Clin Oncol. 2021;39(28):3118–3127. doi: 10.1200/JCO.21.00639. - DOI - PubMed
    1. Slotman B, Faivre-Finn C, Kramer G, Rankin E, Snee M, Hatton M, Postmus P, Collette L, Musat E, Senan S, EORTC Radiation Oncology Group and Lung Cancer Group Prophylactic cranial irradiation in extensive small-cell lung cancer. N Engl J Med. 2007;357(7):664–672. doi: 10.1056/NEJMoa071780. - DOI - PubMed
    1. Takahashi T, Yamanaka T, Seto T, Harada H, Nokihara H, Saka H, Nishio M, Kaneda H, Takayama K, Ishimoto O, Takeda K, Yoshioka H, Tachihara M, Sakai H, Goto K, Yamamoto N. Prophylactic cranial irradiation versus observation in patients with extensive-disease small-cell lung cancer: a multicentre, randomised, open-label, phase 3 trial. Lancet Oncol. 2017;18(5):663–671. doi: 10.1016/S1470-2045(17)30230-9. - DOI - PubMed
    1. Wolfson AH, Bae K, Komaki R, Meyers C, Movsas B, Le Pechoux C, Werner-Wasik M, Videtic GM, Garces YI, Choy H. Primary analysis of a phase II randomized trial Radiation Therapy Oncology Group (RTOG) 0212: impact of different total doses and schedules of prophylactic cranial irradiation on chronic neurotoxicity and quality of life for patients with limited-disease small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2011;81(1):77–84. doi: 10.1016/j.ijrobp.2010.05.013. - DOI - PMC - PubMed
    1. Monje M, Mizumatsu S, Fike J, et al. Irradiation induces neural precursor-cell dysfunction. Nat Med. 2002;8:955–962. doi: 10.1038/nm749. - DOI - PubMed

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