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Comment
. 2022 Mar;48(3):372-373.
doi: 10.1007/s00134-021-06613-w. Epub 2022 Jan 13.

Choice of priors: how much scepticism is appropriate?

Anders Granholm  1   2 , Marie Warrer Munch  3   4 , Morten Hylander Møller  3   4 , Theis Lange  5 , Anders Perner  3   4
Affiliations
Comment

Choice of priors: how much scepticism is appropriate?

Anders Granholm et al. Intensive Care Med. 2022 Mar.
No abstract available

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Comment on

  • Dexamethasone 12 mg versus 6 mg for patients with COVID-19 and severe hypoxaemia: a pre-planned, secondary Bayesian analysis of the COVID STEROID 2 trial.
    Granholm A, Munch MW, Myatra SN, Vijayaraghavan BKT, Cronhjort M, Wahlin RR, Jakob SM, Cioccari L, Kjær MN, Vesterlund GK, Meyhoff TS, Helleberg M, Møller MH, Benfield T, Venkatesh B, Hammond NE, Micallef S, Bassi A, John O, Jha V, Kristiansen KT, Ulrik CS, Jørgensen VL, Smitt M, Bestle MH, Andreasen AS, Poulsen LM, Rasmussen BS, Brøchner AC, Strøm T, Møller A, Khan MS, Padmanaban A, Divatia JV, Saseedharan S, Borawake K, Kapadia F, Dixit S, Chawla R, Shukla U, Amin P, Chew MS, Wamberg CA, Gluud C, Lange T, Perner A. Granholm A, et al. Intensive Care Med. 2022 Jan;48(1):45-55. doi: 10.1007/s00134-021-06573-1. Epub 2021 Nov 10. Intensive Care Med. 2022. PMID: 34757439 Free PMC article. Clinical Trial.
  • Pick your prior: scepticism about sceptical prior beliefs.
    de Grooth HJ, Elbers P. de Grooth HJ, et al. Intensive Care Med. 2022 Mar;48(3):374-375. doi: 10.1007/s00134-021-06602-z. Epub 2021 Dec 17. Intensive Care Med. 2022. PMID: 34919155 Free PMC article. No abstract available.

References

    1. Granholm A, Munch MW, Myatra SN et al (2021) Dexamethasone 12 mg versus 6 mg for patients with COVID-19 and severe hypoxaemia: a pre-planned, secondary Bayesian analysis of the COVID STEROID 2 trial. Intensive Care Med. https://doi.org/10.1007/s00134-021-06573-1 - DOI - PubMed - PMC
    1. Granholm A, Munch MW, Myatra SN et al (2021) Higher vs lower doses of dexamethasone in patients with COVID-19 and severe hypoxia (COVID STEROID 2) trial: protocol for a secondary Bayesian analysis. Acta Anaesthesiol Scand 65:702–710 - DOI
    1. COVID STEROID 2 Trial Group (2021) Effect of 12 mg vs 6 mg of dexamethasone on the number of days alive without life support in adults with COVID-19 and severe hypoxemia: the COVID STEROID 2 randomized trial. JAMA 326:1807–1817 - DOI
    1. de Grooth H, Elbers P (2021) Pick your prior: scepticism about sceptical prior beliefs. Intensive Care Med. https://doi.org/10.1007/s00134-021-06602-z - DOI - PubMed - PMC
    1. Zampieri FG, Casey JD, Shankar-Hari M, Harrell FE Jr, Harhay MO (2021) Using Bayesian methods to augment the interpretation of critical care trials. an overview of theory and example reanalysis of the alveolar recruitment for acute respiratory distress syndrome trial. Am J Respir Crit Care Med 203:543–552 - DOI

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